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Cellular Backpacks for Drug Delivery Across the Blood-Brain Barrier

Technology / Case number: #18547J
Robert Cohen / Natalya Klyachko / Yuling Zhao / Matthew Haney / Elena Batrakova / Roberta Polak / Michael F Rubner
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Processing of High-Capacity Low-Tortuosity Thick Electrodes for Lithium Ion-Batteries

Technology / Case number: #18886J
Yet-Ming Chiang / Linsen Li / Randall Erb / Jonathan Sander
Technology Areas: Energy & Distribution
Impact Areas: Advanced Materials
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A Metal-Organic Framework Electrode for Li-Ion Supercapacitors

Technology / Case number: #21224J
Mircea Dinca / Harish Banda / Riccardo Parenti / Michal Borysiewicz / Jinhu Dou
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Multiscale Porous High-Temperature Heat Exchanger

Technology / Case number: #21240J
Evelyn N. Wang / Rodrigo Guerra / Olivia Brandt / Chad Wilson / Rodney Trice / Jeffrey Youngblood / Xiangyu Li / Lenan Zhang / Kyle Wilke / Arny Leroy / Bikramjit Bhatia / Lin Zhao
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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P3MT/Horizontally-Aligned CNT Nanocomposite for Supercapcitor with High Areal Capacitance

Technology / Case number: #21425J
Karen Gleason / Yosef (Yosi) Stein / Xiaoxue Wang / Yue Zhou / Estelle Cohen / Brian L Wardle
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Metal-Halogen Batteries using Immiscible Solvents

Technology / Case number: #21901V
Yet-Ming Chiang / Fei Wang / Andres Badel
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Enhancement of Lignocellulosic Fermentation in S. Cerevisiae by Combined Genetic Modulations and Media Supplementation

Technology / Case number: #21982WJ
Gerald Fink / Felix Lam / Gregory Stephanopoulos
Technology Areas: Biotechnology / Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future
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Facile Preparation of Flame-Retardant, Non-Toxic Phosphate Ester Ionic Liquid Electrolytes

Technology / Case number: #18800QJ
Christopher Cummins / Shiyu Zhang / Matthew Nava / Daniel Nocera
Technology Areas: Energy & Distribution
Impact Areas: Sustainable Future, Advanced Materials
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Analysis and Design of a Membrane-based Triggering Mechanism for Ingestible Devices

Technology / Case number: #22043
Giovanni Traverso / Torben Sebastia Last / Graham Arrick
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Manually Actuated Device Capable of On-demand/Programmed Pulsatile Drug Delivery

Technology / Case number: #21833JQ
Giovanni Traverso / Qianqian Wan / Adam Wentworth / SeungHo Lee / Rebecca McManus / Jason Li
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Multi-stable Device Configurations and Controls for Gastric Drug Delivery Devices

Technology / Case number: #22017J
Robert Langer / Ludwig Erik Aguilar / Jens Laursen / Kuldeep Sanger / Nikolaj Eusebius Jakobsen / Adam Jun Bohr / Torben Sebastia Last / Yi Lu / Graham Arrick / Declan Gwynne / Jesper Windum / Brian Mouridsen / Jacob Wainer / Morten Frederiksen / Niclas Roxhed / Giovanni Traverso
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Flexible Electronics for Analyte Detection

Technology / Case number: #21994JQ
Robert Langer / Luca Di Tizio / Sean You / Hen Wei Huang / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Flower-Inspired System with Shape-Memory Torsion Springs

Technology / Case number: #20940J
Robert Langer / Simo Pajovic / Sahab Babaee / Ester Caffarel Salvador / Giovanni Traverso
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Biodegradable Polymers for Messenger RNA Delivery to the Lung

Technology / Case number: #19314
Daniel Anderson / Asha Patel / James Kaczmarek / Kevin Kauffman
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Structure-Guided Chemical Modification of Guide RNA and its Applications

Technology / Case number: #19175V
Robert Langer / Hao Yin / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Derivation of Enteroendocrine Cells and Insulin Expressing Cells

Technology / Case number: #18445J
Robert Langer / Xiaolei Yin / Jeffrey Michael Karp
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Implantable Devices and Methods for Evaluation of Active Agents

Technology / Case number: #17867J
No Inventor / John Santini / Oliver Jonas / Jason Fuller / Robert Tepper
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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sgRNA Chemical Modification for Efficient Gene Editing

Technology / Case number: #17805V
Robert Langer / Hao Yin / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Fully Implantable, Autonomous Closed-Loop System Capable of Long-Term Vital Signs Monitoring and Performing Lifesaving Treatment

Technology / Case number: #23387J
Anantha Chandrakasan / Ian Ballinger / Tom Kerssemakers / Peter Chai / Saurav Maji / SeungHo Lee / Hen Wei Huang / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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Pore Creation Methods in Monolayer Graphene for Membrane Applications

Technology / Case number: #18915J
Jing Kong / Sui Zhang / Ahmed Ibrahim / Piran Kidambi / Tahar Laoui / Rohit N Karnik
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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