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Using Gamma Sensory Entriainment to Rescue Brain Development Defects in Down Syndrome

Technology / Case number: #26448P
Li-Huei Tsai / Md Rezaul Islam / Dong Shin Park
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Rational Mutants of Bxb1 Derived from Structural Insights

Technology / Case number: #25675J
Omar Abudayyeh / Teppei Soma / Masahiro Hiraizumi / Christopher Fell / Hiroshi Nishimasu / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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L-SOMA: Oral Delivery of a Biologic Molecule to the Stomach Wall via a Liquid Injection

Technology / Case number: #21194QJ
Robert Langer / Andreas Vegge / Jorrit Jeroen Water / Xiaoya Lu / Mikkel Wennemoes Hvitfeld Ley / Brian Jensen / Mette Poulsen / Jesper Windum / Brian Mouridsen / Mikkel Oliver Jespersen / Morten Frederiksen / Alex Abramson / Giovanni Traverso
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Apparatus, Systems and Methods For Continuous RNA Manufacturing

Technology / Case number: #26430J
Allan S. Myerson / Marianna Sofman / Richard D Braatz
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Novel Fabrication Method for Hydrogel-coated Heat Exchangers for Energy and Water Applications

Technology / Case number: #26047
Bachir El Fil / Joseph Phelim Mooney / Liliosa Cole / Carlos Diaz Marin
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future, Advanced Materials
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Epigenetic Positive Feedback Loop to Mitigate Transgene Silencing in Mammalian Cells

Technology / Case number: #26152
Sebastian Palacios / Elia Salibi / Domitilla Del Vecchio
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Ultra-Thin Conformal Coating Device for Cell Therapy

Technology / Case number: #26281J
Giovanni Traverso / Henry Trainor / Boram Kim / Jong Seung Lee / Nabil Shalabi / Matt Murphy / Troy Ziliang Kang
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Isolated Piezoelectric-Resonator-Based Converter and Devices

Technology / Case number: #26405
Jeffrey Lang / Daniel Brown / Amanda Jackson / David J Perreault
Technology Areas: Electronics & Photonics / Energy & Distribution / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Sustainable Future, Connected World, Advanced Materials
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Rapid Swap Battery System

Technology / Case number: #26407
Alexander Slocum / David Edington / Abigail Wucherer / Aditya Mehrotra
Technology Areas: Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Sustainable Future, Connected World
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Peptide-Polyanion Conjugate to Activate STING Innate Immune Signaling

Technology / Case number: #26286
Paula Hammond / Justin Kaskow
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Devices for Needless Drug Delivery in the GI tract

Technology / Case number: #21911QJ
Robert Langer / Adam Jun Bohr / Aghiad Ghazal / Drago Sticker / Cody Cleveland / Torben Sebastia Last / Yi Lu / Graham Arrick / Declan Gwynne / Sean You / Jacob Wainer / Niclas Roxhed / Giovanni Traverso
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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An Energy-Efficient, Adiabatic Electrode Stimulator with Inductive Energy Recycling and Feedback Current Regulation

Technology / Case number: #14859
Rahul Sarpeshkar / Scott Arfin
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Energy & Distribution
Impact Areas: Healthy Living
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Supramolecular PEGylation of Protein Therapeutics

Technology / Case number: #18077
Robert Langer / Eric Appel / Matthew Webber / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Flexible and Implantable Glucose Fuel Cell

Technology / Case number: #16172L
Rahul Sarpeshkar / Michale S Fee / Benjamin Rapoport / Jakub Kedzierski / Todd Thorsen / Jeremy Muldavin
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Energy & Distribution / Sensing & Imaging
Impact Areas: Healthy Living
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Impurity-Resilient Electrodes for CO2 Capture in Ocean Water

Technology / Case number: #26451
T. Alan Hatton / David Kim / Fabian Dickhardt / Michael Nitzsche / Kripa K Varanasi
Technology Areas: Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Engineered Binding Proteins that Specifically Target Bacteria

Technology / Case number: #22368
Hadley Sikes / Yining Hao / Ki-Joo Sung
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Collapsible Library Design to Enable Characterization of Hyperdiverse Peptide Libraries

Technology / Case number: #26377J
Bradley L. Pentelute / Dimuthu Vithanage / Corey Johnson / John Albin / Gha Young Lee / Wayne Vuong
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Fanzors are RNA-Guided Nucleases Encoded in Eukaryotic Genomes

Technology / Case number: #24942
Omar Abudayyeh / Kaiyi Jiang / Justin Lim / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Machine Learned Chemical Intuition for the AI Generation of Molecules within Specific Chemical Spaces

Technology / Case number: #26403
Brett McGuire / Zachary Fried
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Oxygen-Generating Scaffolds for Stem Cell Depot Support

Technology / Case number: #24650J
Giovanni Traverso / Young-Geun Park
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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