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Perfusable Host Microfluidic Endothelial Networks for Spheroid and Organoid Co-culture and Immune Cell Infiltration Studies

Technology / Case number: #22749
Roger Kamm / Huu Tuan Nguyen / Sharon Lee
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Closed-Loop System for Blood Pressure Control

Technology / Case number: #22797
Emery Brown / Taylor Baum
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science
Impact Areas: Healthy Living
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A Fluidic Platform for Perfusable Vascularized Tumor Spheroids and Organoids

Technology / Case number: #22942
Roger Kamm / Zhengpeng Wan / Shun Zhang
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Lung-Cancer Specific T Cell Dysfunction

Technology / Case number: #23004
John Love / Stefani Spranger / Brendan Horton / Duncan Morgan / Karl Wittrup
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Method Leveraging Morphology for Non-Destructive In Situ Mechanical Characterization of Heterogeneous Biological Tissue

Technology / Case number: #23018
Elazer Edelman / Max Olender / David Marlevi / Farhad Rikhtegar Nezami / Bharath Narayanan
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Bottlebrushed Polyurethane for Tough Organogel

Technology / Case number: #23187
Xuanhe Zhao / Xinyue Liu / Xiaoyu Chen
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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A Machine Learning Platform for Diverse Applications in Drug Discovery and Delivery

Technology / Case number: #23916HM
Edward Boyden / Chi Zhang / Tay Won Shin
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Healthy Living
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Method and Apparatus for Inferring Elevated Pulmonary Capillary Wedge Pressures from Single-Lead Electrocardiogram Telemetry Data

Technology, Software / Case number: #23955J
Daphne Schlesinger / Md Ridwanul Alam / Eugene Pomerantsev / Collin Stultz
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Intrinsically Stretchable Microelectronic Fibers and Their Assemblies as Multifunctional Bioelectronic Interfaces for Whole Organs

Technology / Case number: #24178
Polina Anikeeva / Atharva Sahasrabudhe / Rajib Mondal
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Tissue-integrating Neural Interfaces

Technology / Case number: #24351
Polina Anikeeva / Anthony Tabet
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Non-Fibrotic Implantable Devices on Diverse Organs

Technology / Case number: #24648
Xuanhe Zhao / Hyunwoo Yuk / Jingjing Wu / Jue Deng
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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System and Methods for Noninvasive Point-of-Care Intracranial Pressure, Intracranial Compliance, and Cerebrovascular Resistance Measurement

Technology / Case number: #24678
Thomas Heldt / Syed Imaduddin / Charles Sodini
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Constriction-Minimizing Microfluidic Devices Enabling Co-Culture in Engineered Hydrogels

Technology / Case number: #24723P
Li-Huei Tsai / Robert Langer / Alice Stanton
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Hybrid Hydrogel to Support 3D Culture of Primary Human Cells

Technology / Case number: #25192
Linda Griffith / Samantha Holt
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Machine Learning-guided Whole-Organ Optical Imaging Technique for Non-destructive Identification of Early Pre-Cancer Lesions and Harvesting of Viable Cells from the same for Organoid Culture

Technology / Case number: #25480
Neelkanth Bardhan / Vivek Rastogi / Angela Belcher
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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Hyperlactatemia Prediction

Technology / Case number: #18128J
Andrew Reisner / Thomas Heldt / Michael Filbin / Max Dunitz / George Verghese
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Computer Science
Impact Areas: Healthy Living
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System and Method for Automated Ovarian Follicular Monitoring

Technology / Case number: #19173PJ
Emery Brown / Rose Faghih / Aaron Styer
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Communication Systems / Computer Science
Impact Areas: Healthy Living
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Emboli Detection Methods to Identify Stroke Mechanism or Stroke Risk in Susceptible Adults and Children

Technology, Software / Case number: #21233J
Thomas Heldt / Syed Imaduddin / Kerri LaRovere / Barry Kussman
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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A Multimodal Metric for Tracking Nociception Under Anesthesia

Technology / Case number: #20522J
Emery Brown / Riccardo Barbieri / Sandya Subramanian
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Minimally Invasive Electroceutical Catheters

Technology / Case number: #22483J
Ellen Roche / Terry Steele / Manisha Singh
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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