System and Methods for Noninvasive Point-of-Care Intracranial Pressure, Intracranial Compliance, and Cerebrovascular Resistance Measurement

Systems and methods related to determination of patient parameters such as intracranial pressure (ICP), intracranial compliance (ICC), and cerebrovascular resistance (CVR) are provided. In some instances, the parameters are determined based at least in part on measures two or more parameters related to distension of a vessel and blood flow through the vessel (e.g., arterial blood pressure and cerebral blood flow). In some instances, the parameters are determined based at least in part on measurements performed using one or more probes (e.g., a single probe) at a single patient site. The systems and method described may, in some instances, facilitate determination of these parameters non-invasively and/or at a point-of-care.