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Engineered Synthetic IRES with Improved and Robust Translation in Circular RNA

Technology / Case number: #25300YJ
James Collins / Nayoung Kim / Yu Li / Makoto Lalwani / Xiaoyu Chen / Kehan Zhang / Shiva Razavi / Katherine Ilia
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Lipid Anchorage of Cytokines onto Layer-by-Layer Nanoparticles

Technology / Case number: #25070H
Darrell J Irvine / Ivan Pires / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Clockwise Learning Task

Technology / Case number: #25128M
Ann M. Graybiel / Georgios Papageorgiou
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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Cell-Surface Anchored Cytokine Therapy

Technology, Tangible Property / Case number: #25245H
Darrell J Irvine / Luciano Santollani / Karl Dane Wittrup
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Latent-Fluoride Containing Polymers for Triggered Degradation

Technology / Case number: #23066
Jeremiah A. Johnson / Christopher Brown / Peyton Shieh
Technology Areas: Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Spatially Localized Gene Delivery of Adeno-Associated Viruses

Technology / Case number: #25055
Polina Anikeeva / Keisuke Nagao
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Reconstituted Lipoprotein Particles to Rescue Lipid Defects in the Alzheimer's Brain

Technology / Case number: #25445P
Li-Huei Tsai / Rebecca Pinals
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Method of Enhanced Clearance of Uremic Toxins in Hemodialysis using Nanoporous Membranes

Technology / Case number: #21853
Rohit N Karnik / Chi Cheng / Chun Man Chow / Aaron Persad
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Scalable Ultra Low Latency Photonic Tensor Processor

Technology / Case number: #23088
Dirk R Englund / Alexander Sludds / Liane Sarah Bel Bernstein
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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Deep Context Maps

Technology / Case number: #22949
Daniela Rus / Arjun Gupta / Igor Gilitschenski / Sertac Karaman / Guy Rosman
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living, Connected World
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Optimized Alum-Anchored HIV Env Immunogens

Technology / Case number: #24972HJ
Darrell J Irvine / William Schief / Jon Steichen / Christopher Cottrell / Kristen Rodrigues
Technology Areas: Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Variable Compression Human-Machine Interface Cuff

Technology / Case number: #21776
Neville Hogan / Gabrielle Enns / James Hermus / Meghan Huber
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Carbon-based Non-volatile Memristors

Technology / Case number: #21953
Pablo Jarillo-Herrero / Zhiren Zheng / Suyang Xu / Nuh Gedik / Qiong Ma
Technology Areas: Computer Science
Impact Areas: Healthy Living, Sustainable Future
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Translational Hearing Aides for Older Adults

Technology / Case number: #24962
Harry Asada / Ravi Tejwani
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology
Impact Areas: Healthy Living
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A Framework for Using External Contact Features to Enhance Robotic Manipulation Dexterity

Technology / Case number: #20776
Nikhil Chavan Dafle / Rachel Holladay / Alberto Rodriguez
Technology Areas: Biotechnology / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Microscale Photoacoustic Spectroscopy and Microscopy

Technology / Case number: #21078
Anuradha Murthy Agarwal / Robin Singh / Brian Anthony
Technology Areas: Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living
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Realizing Private and Practical Pharmacological Collaboration

Technology / Case number: #21186
Bonnie Berger / Hyunghoon Cho / Brian Hie
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Delivery
Impact Areas: Healthy Living, Uncharted Frontiers
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Automation Calibration of Eye Movements & Pupillometry Measurement using Electrooculogram

Technology / Case number: #21575L
Jeffrey Palmer / Jason Nezvadovitz / Hrishikesh Rao
Technology Areas: Computer Science / Electronics & Photonics
Impact Areas: Healthy Living, Connected World
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Synthesis of Novel Poly(ester urea)s for Drug Delivery

Technology / Case number: #23956
Bradley D. Olsen / Katharina Fransen / Hursh Sureka
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Selective Valorization of Biomass Sugars

Technology / Case number: #21846
Alison Wendlandt / Hayden Carder / Yong Wang
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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