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A Fully Implantable, Autonomous Closed-Loop System Capable of Long-Term Vital Signs Monitoring and Performing Lifesaving Treatment

Technology / Case number: #23387J
Anantha Chandrakasan / Ian Ballinger / Tom Kerssemakers / Peter Chai / Saurav Maji / SeungHo Lee / Hen Wei Huang / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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User-Friendly and Easily-Accessible Synthetic Hydrogels for Biomaterials Application

Technology / Case number: #20694
Robert Langer / Marion Paolini / Jason Andresen / Owen Fenton
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Matching Individual Using Genetic Data for Risk Prediction

Technology / Case number: #19308PQ
Manolis Kellis / Sandeep Nuckchady / Dianbo Liu / Anne Kim / Lauren Huang / Zhizhuo Zhang
Technology Areas: Computer Science
Impact Areas: Healthy Living
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Thermo-Responsive, Inflammation-Targeting (TRIT) Hydrogel Formulations for Local Drug Delivery in Intestinal Inflammation

Technology / Case number: #19181J
Robert Langer / Joshua Korzenik / Ashok Kakkar / Sufeng Zhang / Giovanni Traverso
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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A Generalizable, High-Throughput Method to Rapidly add Chemical Moieties to a Small Molecule Library

Technology / Case number: #22196J
Angela Koehler / Chia-fu Chang / Christina Woo / Sebastian Pomplun / Catherine Henry / Jasmin Kruell / Brice Curtin
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Small Molecule Inhibitors of Interleukin-4

Technology / Case number: #22186J
Angela Koehler / Sean Quinnell / Daniel Sheehy / Luke Ceo / Kelly Tan / Stephen Nestor / Becky Leifer / Shelby Doyle / Arturo Vegas
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Tough Hydrogel Pills Inflating 100 Times in Volume Within 10 Min

Technology / Case number: #20059
Xuanhe Zhao / Xinyue Liu / German Parada Hernandez / Hyunwoo Yuk / Shaoting Lin
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Gastric Residence Electronics

Technology / Case number: #20092J
Robert Langer / Yong Lin Kong / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems
Impact Areas: Healthy Living
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Chimeric Degraders of Cyclin Dependent Kinase 9 with Potential Use for Cancer Therapy

Technology / Case number: #22028
Angela Koehler / Mohammed Toure / Florian Kabinger / Julie Urgiles / Andre Richters
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Macro-Devices for Ultra-Long Residence and Large-Dose Drug Delivery in Stomach

Technology / Case number: #20938JQ
Robert Langer / Jiuyun Shi / Simo Pajovic / Sahab Babaee / Giovanni Traverso
Technology Areas: Biotechnology / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Microelectromechanical Systems for Acoustics

Technology / Case number: #19512
Jeffrey Lang / Apoorva Murarka / Vladimir Bulovic
Technology Areas: Biotechnology / Chemicals & Materials / Electronics & Photonics
Impact Areas: Healthy Living, Advanced Materials
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Systems for Electrical Stimulation

Technology / Case number: #20707JQ
Robert Langer / David Dellal / Alex Abramson / Giovanni Traverso
Technology Areas: Biotechnology / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Hybrid Materials with Living Cells and Tough Hydrogels

Technology / Case number: #18548
Timothy K Lu / Tzu-Chieh Tang / Xinyue Liu / Eleonore Tham / Xuanhe Zhao
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Retrieval Systems for Gastric Resident Systems

Technology / Case number: #20382JQ
Robert Langer / Macy Castaneda / Feyisope Eweje / Niclas Roxhed / Malvika Verma / Giovanni Traverso
Technology Areas: Biotechnology / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Flexible Piezoelectric Devices for Gastrointestinal Motility Sensing

Technology / Case number: #19910JQ
Robert Langer / Canan Dagdeviren / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living, Advanced Materials
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Pooled Screening Identifies Genomic Features (Biomarkers) Modulating Nanoparticle-Cell Interactions

Technology / Case number: #22785J
Paula Hammond / Joelle Straehla / Natalie Boehnke / Angela Koehler
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Magnetically Steerable, Soft-Bodied Continuum Robots

Technology / Case number: #21435
Xuanhe Zhao / Yoonho Kim
Technology Areas: Biotechnology / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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Single Administration, Multi-Dose, Multi-Therapeutic Capable Delivery Platform for Veterinary Applications

Technology / Case number: #20943J
Robert Langer / Tiffany Hua / Miguel Jimenez / Jason Li / Jacob Coffey / Michael Williams / Christoph Winfried Johannes Steiger / Ester Caffarel Salvador / Alex Abramson / Giovanni Traverso
Technology Areas: Agriculture & Food / Biotechnology
Impact Areas: Healthy Living, Advanced Materials
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Cationic Lipidoids and Their Uses for Immunotherapy

Technology / Case number: #19803
Daniel Anderson / Lei Miao / Yuxuan Huang / Linxian Li
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Synthesis of Ester, Carbonate, and Carbamate-derived Novel Biodegradable Ionizable Lipids from Methyl Ricinoleate or Methyl 12-Hydroxystearate and its Applications

Technology / Case number: #23381Q
Daniel Anderson / Jacob Witten / rajith manan / Akiva Gordon / Bowen Li / Luke Rhym
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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