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Biodegradable Lipid-Like Materials for Applications in siRNA Delivery

Technology / Case number: #15420
Robert Langer / Joseph Dorkin / Yunlong Zhang / Arturo Vegas / Kathryn Whitehead / Daniel Anderson
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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High-Repetition-Rate Guided-Mode Femtosecond Laser

Technology / Case number: #13277
Erich P. Ippen / Dominik Pudo / Hyunil Byun / Jian Chen / Franz Kaertner
Technology Areas: Communication Systems / Electronics & Photonics
Impact Areas: Healthy Living, Connected World
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Raman Spectroscopy Based Sensitive and Specific Detection of Alternate Glycemic Markers, Glycated Hemoglobin (HbA1c) and Glycated Albumin for Longterm Diabetes Monitoring

Technology / Case number: #15295
Ramachandra Dasari / Jeon Woong Kang / Narahara Dingari / Ishan Barman
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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2-Aminoindole-Class Antimalarials

Technology / Case number: #14097BJ
Jon Clardy / Elyse Bourque / Yibin Xiang / Renato Skerlj / Edmund Sybertz / Joseph Cortese / Mary Lynn Baniecki / Roger Wiegand / Dyann Wirth / Cassandra Celatka / Sameer Urgaonkar / Ralph Mazitschek
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Hydrophobic Polycationic Coatings That Inhibit Biofilm Formation on Orthopedic Implants and Support Healing During Infection in Sheep

Technology / Case number: #15031J
Alexander Klibanov / Suzanne Stewart / Thomas Schaer / Bryan Hsu
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Healthy Living
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CMOS Readout Circuit Architecture for Large-Format Small-Pixel Photon Counting Focal Plane Arrays Using Geiger-Mode Avalanche Photodiodes

Technology / Case number: #13765L
Brian Aull / Daniel Schuette / Matthew Renzi / Robert Reich
Technology Areas: Electronics & Photonics / Sensing & Imaging
Impact Areas: Climate Stabilization, Healthy Living
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Imidazole-Based Random Co-Polymer for Synthesis of Water Soluble Biocompatible Semiconductor Nanocrystals

Technology / Case number: #13877
Moungi G Bawendi / Peter Allen / Wenhao Liu / Numpon Insin
Technology Areas: Chemicals & Materials / Diagnostics / Electronics & Photonics
Impact Areas: Healthy Living
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Articulating Protective System for Resisting Mechanical Loads

Technology / Case number: #14279
Mary Boyce / Steffen Reichert / Juha Song / Christine Ortiz
Technology Areas: Industrial Engineering & Automation
Impact Areas: Healthy Living, Connected World
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System for Accelerating Parallel Magnetic Resonance Imaging Reconstruction Using Joint Estimation with a Sparse Signal Model

Technology / Case number: #15457J
Vivek Goyal / Leo Grady / Daniel Weller / Lawrence Wald
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Reduction of Maximum Local Specific Absorption Rate via Pulse Multiplexing

Technology / Case number: #13365
Elfar Adalsteinsson / Kawin Setsompop / Adam Zelinski / Vivek Goyal
Technology Areas: Sensing & Imaging
Impact Areas: Healthy Living, Connected World
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1,3,5-triazinane-2,4,6-trione (TNT) Derivatives and Uses Thereof

Technology / Case number: #15446
Robert Langer / Hao Yin / Akinleye Alabi / Joseph Dorkin / Ahmed Eltoukhy / Yizhou Dong / Delai Chen / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Dynamic Nuclear Polarization with Rigid Biradicals

Technology / Case number: #13595JQ
Robert Guy Griffin / Francois Le Moigne / Hakim Karoui / Olivier Ouari / Thorsten Maly / Yoh Matsuki / Paul Tordo
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Heterocycle-Modified Quinolines for Fluorescence-Based Protein Kinase Sensing

Technology / Case number: #13876
Barbara Imperiali / Juan Gonzalez Vera / Elvedin Lukovic
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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SNAPPLE - Sequencing-Mediated Numerical Analysis of Parallel Proximity Ligation Events

Technology / Case number: #13615B
Andreas Gnirke / Daniel Aird / Erez Lieberman
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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A Novel Injectable Thiol-Acrylate Poly(ethylene Glycol) Hydrogel for Sustained Release of Methylprednisolone Sodium Succinate

Technology / Case number: #14439J
Robert Langer / Jonathan Slotkin / Francis Reynolds / Timothy O'Shea / Daniel Siegwart / Christopher Pritchard / Eric Woodard / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Self- Regulated Peptide Hydrogel for Closed Loop Insulin Delivery

Technology / Case number: #15056J
Robert Langer / Alex Aimetti / Zhen Gu / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Methods for Microbial Oil Overproduction via Amplification of the Biosynthetic and Sequestration Pathways Individually or in Combination

Technology / Case number: #15152
Gregory Stephanopoulos / Sagar Chakraborty / Mitchell Tai
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Translocation of Non-Natural Chemical Entities Through Anthrax Protective Antigen Pore

Technology / Case number: #15639J
Bradley L. Pentelute / R. Collier / Gizem Akcay / Jingjing Ling / Amy Rabideau / Xiaoli Liao
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Glucose-Responsive Insulin Formulations Using Chemically Modified Insulin Derivatives and Non-Covalent Insulin-Binding Molecules

Technology / Case number: #15976J
Robert Langer / Rosemary Kanasty / Matthew Webber / Kun Xue / Hung-Chieh (Danny) Chou / Benjamin Tang / Yunlong Zhang / Yair Levi / Arturo Vegas / Daniel Anderson
Technology Areas: Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living
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Self Assembled RSV Nanoparticle Vaccines

Technology / Case number: #16549
Ram Sasisekharan / Aditya Raguram / Vidya Subramanian
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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