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Hardware Models of Biochemical Reaction Networks

Technology / Case number: #13076
Rahul Sarpeshkar
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Colloidal Hydrogel Particles with tunable Chemistry, Geometry, and Flexibility

Technology / Case number: #13461J
Mehmet Toner / Ramin Haghgooie / Daniel Pregibon / Patrick Doyle
Technology Areas: Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Methods for Microbial Oil Overproduction via Amplification of the Biosynthetic and Sequestration Pathways Individually or in Combination

Technology / Case number: #15152
Gregory Stephanopoulos / Sagar Chakraborty / Mitchell Tai
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Translocation of Non-Natural Chemical Entities Through Anthrax Protective Antigen Pore

Technology / Case number: #15639J
Bradley L. Pentelute / R. Collier / Gizem Akcay / Jingjing Ling / Amy Rabideau / Xiaoli Liao
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Glucose-Responsive Insulin Formulations Using Chemically Modified Insulin Derivatives and Non-Covalent Insulin-Binding Molecules

Technology / Case number: #15976J
Robert Langer / Rosemary Kanasty / Matthew Webber / Kun Xue / Hung-Chieh (Danny) Chou / Benjamin Tang / Yunlong Zhang / Yair Levi / Arturo Vegas / Daniel Anderson
Technology Areas: Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living
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Distinct Gene Systems Mediating Activity-Dependent Plasticity in Visual Cortex

Technology / Case number: #11841P
Mriganka Sur / Gabriel Kreiman / Daniela Tropea / Shayan Mukherjee / Alvin Lyckman
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Glucose Valve and Other Metabolite Valves

Technology / Case number: #12369
Tae Moon / Kevin Solomon / Kristala L Jones Prather
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Reverse Micelle Nanoprecipitation: A Method for Encapsulating Nucleic Acids in Biodegradable Polymers

Technology / Case number: #12561J
Robert Langer / Liangfang Zhang / Aleksandar Radovic-Moreno / Omid Farokhzad
Technology Areas: Chemicals & Materials / Computer Science / Electronics & Photonics
Impact Areas: Healthy Living, Advanced Materials
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Olfactory Receptor-Based Devices

Technology / Case number: #12776TE
Shuguang Zhang / Liselotte Kaiser / Joanke (Johanna) Bikker Graveland / Brian Cook / Andreas Mershin / Manu Prakash / David Kong / Yael Maguire
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Transcriptional Engineering of Lactobacillus for Improved Lactic Acid Tolerance and Productivity at Low pH

Technology / Case number: #12783
Gregory Stephanopoulos / Daniel Klein-Marcuschamer
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Extension of a Finite Element Framework for Calculation of DNA Nanostructure Solution Shape, Mechanical, and Optical Properties

Technology / Case number: #16421
Klaus-Jurgen Bathe / Oskar Hallatschek / Etienne Boulais / Reza Sharifi Sedeh / Lun Yang / Keyao Pan / Matthew Adendorff / Do-Nyun Kim / Mark Bathe
Technology Areas: Computer Science
Impact Areas: Healthy Living
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Normalization Correction for Inter-Detector Scatter Enhanced Positron Emission Tomography

Technology / Case number: #16136
Shivang Dave / Joaquin Herraiz / Eduardo Lage / Vicente Parot
Technology Areas: Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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Microbial Production of 3,4-Dihydroxybutyrate (DHBA) and 3-Hydroxybutyrolactone (3-HBL) from Glucose

Technology / Case number: #14595
Kristala L Jones Prather / Himanshu Dhamankar / Collin Martin
Technology Areas: Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Protein Retrosplicing Enabled by a Double Ligation Reaction

Technology / Case number: #15368
Bradley L. Pentelute / Rocco Policarpo / Jingjing Ling / Amy Rabideau / Xiaoli Liao
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Using Correlation Structure of Speech Dynamics to Detect Neurophysiological Changes

Technology / Case number: #16517L
Thomas Quatieri / Jim Williamson / Daryush Mehta / Bea Yu / Rachelle Horwitz- Martin / Brian Helfer
Technology Areas: Computer Science
Impact Areas: Healthy Living, Connected World
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Method for Image and Data Segmentation

Technology, Software / Case number: #13701H
H. Seung / Srinivas Turaga / Viren Jain
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Healthy Living, Connected World
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Human Skin Movement and Strain-Field Calculations and Modeling

Technology / Case number: #14811
Dava Newman / Ashley Wessendorf
Technology Areas: Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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Use of Ranking Methods in Machine Learning to Prioritize Chemical Compounds for Drug Discovery

Technology / Case number: #14011
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Healthy Living
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Spatial-Interaction-Map (SIM): prediction of Critical Residues for Protein-Protein Binding

Technology / Case number: #15203J
Bernhardt Trout / Neeraj Agrawal / Bernhard Helk
Technology Areas: Computer Science
Impact Areas: Healthy Living
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A Computational Procedure for Detection of Sleep Apnea in Children

Technology / Case number: #14463
Chi-Sang Poon / Eliot Katz / Zhi-De Deng
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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