Spatial-Interaction-Map (SIM): prediction of Critical Residues for Protein-Protein Binding

The present disclosure relates to methods and computational tools based, at least in part, on computer simulations that identify hot-spot amino acid residues and binding-region amino acid residues of a protein.

Researchers

Bernhard Helk / Neeraj Agrawal / Bernhardt Trout

Departments: Department of Chemical Engineering
Technology Areas: Computer Science: Bioinformatics
Impact Areas: Healthy Living

  • methods to identify amino acid residues involved in macromolecular binding and uses therefor
    United States of America | Granted | 10,431,325

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