Ellen Roche

Associate Professor

Department
Department of Mechanical Engineering
Technology Areas
Biotechnology: Tissue Engineering, Biomedical Devices & Systems, Sensors & Monitoring / Chemicals & Materials: Polymers, Nanotechnology & Nanomaterials / Industrial Engineering & Automation: Robotics / Drug Delivery: Microparticles & Nanoparticles / Therapeutics: Regenerative Medicine / Sensing & Imaging: Imaging / Biomaterials & Bioelectronics: Tissue Repair, Health Monitoring / Artificial Intelligence (AI) and Machine Learning (ML)

Advancing cardiac device innovation through disruptive technologies such as soft robotics and biodegradable adhesives, directing the Therapeutic Technology Design and Development Lab at MIT.

Background and Experience

Ellen Roche is currently the Latham family Associate Professor at the Institute for Medical Engineering and Science and the Department of Mechanical Engineering at MIT. She directs the Therapeutic Technology Design and Development Lab.  She completed her PhD at Harvard University School of Engineering and Applied Sciences. Her research focuses on applying innovative technologies to the development of cardiac devices. Her research includes development of novel devices to repair or augment cardiac function using disruptive approaches such as soft robotics, combination of mechanical actuation with delivery of cell therapy, and use of light activated biodegradable adhesives. Dr. Roche was employed in the medical device industry for over five years as a research and development engineer and employs her understanding of the medical device industry and the regulatory pathways to medical device commercialization in her academic research. She holds 5 issued patents, with 8 pending and is the authors of over 60 conference/journal papers. She is the recipient of multiple awards including the Fulbright International Science and Technology Award, the Welcome Trust Seed Award in Science, a National Science Foundation CAREER Award, a Charles H. Hood Award for Excellence in Child Health Research and an NIH Trailblazer Award.

Technologies

Patient-Specific Benchtop Beating Heart Simulator for Recreating Left Atrial Biomechanics and Hemodynamics for LAA Closure and HFpEF Intervention Testing

Technology / Case number: #25761
Ellen Roche / Manisha Singh / Keegan Mendez
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
License

sEMG Derived Neural Network-Based Motion Prediction Exoskeleton

Technology / Case number: #25254
Ellen Roche / Lonnie Grove Petersen / Bon Koo
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation
Impact Areas: Advanced Materials
License

Soft Robotic, 3D-Printed Simulator of Heart Function and Disease

Technology / Case number: #25013J
Ellen Roche / Debkalpa Goswami / Christopher Nguyen / Sophie Wang / Jean Bonnemain / Luca Rosalia / Caglar Ozturk
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
License

Minimally Invasive Electroceutical Catheters

Technology / Case number: #22483J
Ellen Roche / Manisha Singh / Terry Steele
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
License

A Dynamic Soft Robotic Heart Model Combining Biohybrid Materials

Technology / Case number: #22057J
Xuanhe Zhao / Christopher Nguyen / Clara Park / Ellen Roche / Hyunwoo Yuk
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
License

Catheter for Intracardiac 3D Bioprinting

Technology / Case number: #22338J
Brett E Bouma / Markus Horvath / Sophie Wang / Milen Shishkov / Victor Damptey / Connor Verheyen / Keegan Mendez / Ellen Roche / Sebastien Uzel / Jennifer Lewis
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
License

Fenestration Alignment Program

Technology / Case number: #22841J
Ellen Roche / Marc Schermerhorn / Patric Liang / Tom Dillon
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
License

Implantable device to ensure stoma patency following Endoscopic Third Ventriculostomy Procedure

Technology / Case number: #24977
Ellen Roche / Jonas Sogbadji / Gabriel Friedman / Bryce Starr / Luca Rosalia
Technology Areas: Biotechnology
Impact Areas: Healthy Living
License

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