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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Closed-Loop Noninvasive Brain Stimulation with Simultaneous Imaging to Control Cerebrospinal Fluid Flow in Humans

Technology / Case number: #25482
Laura Lewis / Joshua Levitt
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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Ingestible Electronics Integrated with Flexible Measurement Electrodes for Gastrointestinal Bioelectric Sensing

Technology / Case number: #23241
Carlo Giovanni Traverso / Robert Langer / Siheng You / So-Yoon Yang / Adam Gierlach / George Selsing
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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A Natural Language Diet Tracking Smartphone Application

Software / Case number: #19264
Mandy Korpusik / James Glass
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Communication Systems
Impact Areas: Healthy Living, Connected World
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Machine Learning Model for Diagnosis of Various Pulmonary Diseases -- Logistic Regression

Software / Case number: #22332
Daniel Chamberlain / Christian Infante / Richard Fletcher
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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Machine Learning Model for Diagnosis of Various Pulmonary Diseases -- Bayesian

Software / Case number: #22333
Aneesh Anand / Richard Fletcher
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Computer Science
Impact Areas: Healthy Living
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Signal Processing and Machine Learning Algorithm for Assessing Atherosclerosis and Coronary Arterial Disease from Multi-Site PPG Data

Software / Case number: #22643
Niccolo Pignatelli / Botong Ma / Victoria Ouyang / Richard Fletcher
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Computer Science
Impact Areas: Healthy Living, Uncharted Frontiers
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PPG Pulse Analysis and Signal Processing for Determination of Cardiovascular Risk

Software / Case number: #22644
Niccolo Pignatelli / Victoria Ouyang / Richard Fletcher
Technology Areas: Biomaterials & Bioelectronics / Computer Science
Impact Areas: Healthy Living
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Instructional Materials in Support of: Set of Educational Building Blocks to Model Nucleic Acid Structures

Case number: #20438C
John Vandiver
Technology Areas: Communication Systems / Therapeutics
Impact Areas: Healthy Living, Connected World
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Lipid Compositions for Delivery of Therapeutic Agents Comprising Cationic Lipids

Technology / Case number: #23842J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Compositions and Methods for Inhibiting Expression of the Signal Regulatory Protein Alpha Gene

Technology / Case number: #23695J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Bowen Li / Akiva Gordon / Idris Raji / Daniel Anderson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Quick Release Capsules for Small Intestine Delivery

Technology / Case number: #20105J
Carlo Giovanni Traverso / Daniel Minahan / Alex Abramson / Niclas Roxhed / Ester Caffarel Salvador / David Dellal / Vance Soares / Robert Langer / Christoph Winfried Johannes Steiger / Morten Frederiksen
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Engineering a Swine Macro-Organ Colorectal Cancer Platform to Combat Transport-Induced Chemotherapy Resistance

Technology / Case number: #22864JQ
Carlo Giovanni Traverso / Yunhua Shi / Vance Soares / Daniel Reker / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Closed-Loop Ingestible Robot for Radiation and Chemical Sensing

Technology / Case number: #22735
Carlo Giovanni Traverso / Hen Wei Huang / James Byrne
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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Endovascular Injectable Stents for Cardiovascular Drug Delivery

Technology / Case number: #22578J
Carlo Giovanni Traverso / Sahab Babaee / Mazen Albaghdadi / Mohammed Chowdhury
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living, Advanced Materials
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Ingestible Electronic Pills for Hormone Modulation

Technology / Case number: #22427
Carlo Giovanni Traverso / Khalil Ramadi / James McRae
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Flexible Electronics for Analyte Detection

Technology / Case number: #21994J
Carlo Giovanni Traverso / Robert Langer / Hen Wei Huang / Siheng You / Luca Di Tizio
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Decision System to Avoid and Analyze Excipient-based Adverse Effects

Technology / Case number: #21039JQ
Carlo Giovanni Traverso / Daniel Reker / Robert Langer / Steven Blum
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Tissue Platform and Machine Learning Algorithm for Drug-Drug Transporter Interaction Discovery

Technology / Case number: #21883J
Carlo Giovanni Traverso / Yunhua Shi / Vance Soares / Daniel Reker / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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