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Perfusable Host Microfluidic Endothelial Networks for Spheroid and Organoid Co-culture and Immune Cell Infiltration Studies

Technology / Case number: #22749
Roger Kamm / Huu Tuan Nguyen / Sharon Lee
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Closed-Loop System for Blood Pressure Control

Technology / Case number: #22797
Emery Brown / Taylor Baum
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science
Impact Areas: Healthy Living
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Fenestration Alignment Program

Technology / Case number: #22841J
Ellen Roche / Tom Dillon / Patric Liang / Marc Schermerhorn
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Non-Invasive Tactile Stimulation for Improving Motor Function

Technology / Case number: #22928P
Li-Huei Tsai / Ho-Jun Suk / Guojie Xu / Arit Banerjee
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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A Fluidic Platform for Perfusable Vascularized Tumor Spheroids and Organoids

Technology / Case number: #22942
Roger Kamm / Zhengpeng Wan / Shun Zhang
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Method Leveraging Morphology for Non-Destructive In Situ Mechanical Characterization of Heterogeneous Biological Tissue

Technology / Case number: #23018
Elazer Edelman / Max Olender / David Marlevi / Farhad Rikhtegar Nezami / Bharath Narayanan
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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A Fabrication-Free Microfluidic Device for Scalable, High-Volume Bacterial Electroporation

Technology / Case number: #23552
Cullen Buie / Po-Hsun Huang / Sijie Chen
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Multifunctional Microelectronics Fibers as Implantable Bioelectronic Interfaces for Central and Peripheral Neuromodulation

Technology / Case number: #23751J
Polina Anikeeva / Tural Khudiyev / Atharva Sahasrabudhe / Laura Rupprecht / Diego Bohórquez
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Lateral Flow Assay Quantifying SARS-Cov-2 Neutralizing Antibody Titer

Technology / Case number: #23869
Hojun Li / Guinevere Connelly
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Method and Apparatus for Inferring Elevated Pulmonary Capillary Wedge Pressures from Single-Lead Electrocardiogram Telemetry Data

Technology, Software / Case number: #23955J
Daphne Schlesinger / Md Ridwanul Alam / Eugene Pomerantsev / Collin Stultz
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Intrinsically Stretchable Microelectronic Fibers and Their Assemblies as Multifunctional Bioelectronic Interfaces for Whole Organs

Technology / Case number: #24178
Polina Anikeeva / Atharva Sahasrabudhe / Rajib Mondal
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Tissue-integrating Neural Interfaces

Technology / Case number: #24351
Polina Anikeeva / Anthony Tabet
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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High Throughput Stochastic Bio-Molecular Sensor

Technology / Case number: #24610
Ashwin Gopinath / Swathi Manda
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Drinkable, Tough Hydrogels for Gastrointestinal Applications

Technology / Case number: #24642J
Carlo Giovanni Traverso / Robert Langer / Gary Liu / Matthew Pickett
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Non-Fibrotic Implantable Devices on Diverse Organs

Technology / Case number: #24648
Xuanhe Zhao / Hyunwoo Yuk / Jingjing Wu / Jue Deng
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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System and Methods for Noninvasive Point-of-Care Intracranial Pressure, Intracranial Compliance, and Cerebrovascular Resistance Measurement

Technology / Case number: #24678
Thomas Heldt / Syed Imaduddin / Charles Sodini
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Implantable device to ensure stoma patency following Endoscopic Third Ventriculostomy Procedure

Technology / Case number: #24977
Ellen Roche / Luca Rosalia / Bryce Starr / Gabriel Friedman / Jonas Sogbadji
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Tool for Spatially Targeted Access and Placement of Hardware or Drugs in Deep or Consolidated Tissues

Technology / Case number: #25071
Shriya Srinivasan / Robert Langer / Alexander Madinger
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Mechanisms for Controlled Volume Injection into a Soft Media with Concurrent Pressure Measurement

Technology / Case number: #25109
Nevan Hanumara / Tal Cohen / Alexander Slocum / Brendan Unikewicz / Emily Sologuren / Joseph Morales / Andre Pincot / Sarah Sams
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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A Machine Learning-guided Whole-Organ Optical Imaging Technique for Non-destructive Identification of Early Pre-Cancer Lesions and Harvesting of Viable Cells from the same for Organoid Culture

Technology / Case number: #25480
Neelkanth Bardhan / Vivek Rastogi / Angela Belcher
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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