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sgRNA Chemical Modification for Efficient Gene Editing

Technology / Case number: #17805V
Robert Langer / Hao Yin / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Anti-Zika Virus Antibodies

Technology / Case number: #18525J
Ram Sasisekharan / Subhash Vasudevan / Satoru Watanabe / Kuan Chan / Eng Ooi / Kannan Tharakaraman
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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User-Friendly and Easily-Accessible Synthetic Hydrogels for Biomaterials Application

Technology / Case number: #20694
Robert Langer / Marion Paolini / Jason Andresen / Owen Fenton
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Relativistic Statistical Arbitrage

Technology / Case number: #14247J
Cameron E Freer / Alexander Wissner-Gross
Technology Areas: Communication Systems / Computer Science
Impact Areas: Connected World
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Decoding via Guessing Noise

Technology / Case number: #20169J
Muriel Medard / Kenneth Duffy / Jiange Li
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science
Impact Areas: Uncharted Frontiers
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Decoding by Guessing Noise II

Technology / Case number: #20215J
Muriel Medard / Kenneth Duffy
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science
Impact Areas: Connected World, Advanced Materials
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A Generalizable, High-Throughput Method to Rapidly add Chemical Moieties to a Small Molecule Library

Technology / Case number: #22196J
Angela Koehler / Chia-fu Chang / Christina Woo / Sebastian Pomplun / Catherine Henry / Jasmin Kruell / Brice Curtin
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Small Molecule Inhibitors of Interleukin-4

Technology / Case number: #22186J
Angela Koehler / Sean Quinnell / Daniel Sheehy / Luke Ceo / Kelly Tan / Stephen Nestor / Becky Leifer / Shelby Doyle / Arturo Vegas
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Gastric Residence Electronics

Technology / Case number: #20092J
Robert Langer / Yong Lin Kong / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems
Impact Areas: Healthy Living
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Chimeric Degraders of Cyclin Dependent Kinase 9 with Potential Use for Cancer Therapy

Technology / Case number: #22028
Angela Koehler / Mohammed Toure / Florian Kabinger / Julie Urgiles / Andre Richters
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Electrically Driven Light-Emitting Tunnel Junctions

Technology / Case number: #18393
Jeffrey Lang / Thomas Mahony / Farnaz Niroui / Vladimir Bulovic
Technology Areas: Communication Systems / Sensing & Imaging
Impact Areas: Advanced Materials
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Hybrid Materials with Living Cells and Tough Hydrogels

Technology / Case number: #18548
Timothy K Lu / Tzu-Chieh Tang / Xinyue Liu / Eleonore Tham / Xuanhe Zhao
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Pooled Screening Identifies Genomic Features (Biomarkers) Modulating Nanoparticle-Cell Interactions

Technology / Case number: #22785J
Paula Hammond / Joelle Straehla / Natalie Boehnke / Angela Koehler
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Cationic Lipidoids and Their Uses for Immunotherapy

Technology / Case number: #19803
Daniel Anderson / Lei Miao / Yuxuan Huang / Linxian Li
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Synthesis of Ester, Carbonate, and Carbamate-derived Novel Biodegradable Ionizable Lipids from Methyl Ricinoleate or Methyl 12-Hydroxystearate and its Applications

Technology / Case number: #23381Q
Daniel Anderson / Jacob Witten / rajith manan / Akiva Gordon / Bowen Li / Luke Rhym
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Optical Network Switch for Dynamically Reconfigurable Multicast Topologies

Technology / Case number: #19503L
Dirk R Englund / Gregory Steinbrecher
Technology Areas: Communication Systems / Computer Science
Impact Areas: Connected World
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Base Station Ordering Technique (BoLT) for Localization in Dense Cellular Networks

Technology / Case number: #19869J
Moe Win / Hesham ElSawy / Mohamed-Slim Alouini / Wenhan Dai
Technology Areas: Communication Systems / Computer Science
Impact Areas: Connected World
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Dual Polarized Notch Antenna Having Low Profile Stripline Feed

Technology / Case number: #21017L
Glenn Brigham
Technology Areas: Communication Systems / Computer Science
Impact Areas: Connected World
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Data-Driven Angular Jitter Estimator for Lidar

Technology / Case number: #21433L
Eric Statz / Charles Primmerman / Eric Phelps
Technology Areas: Communication Systems / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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Fiber Based RF Phased-Array Antennas

Technology / Case number: #21616L
Alan Fenn / Lauren Cantley / Sivasubramaniam Yegnanarayanan / Alexander Stolyarov
Technology Areas: Communication Systems / Computer Science
Impact Areas: Connected World
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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