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Slow Delivery of Antigen and Adjuvant Plus A Delayed Boost for Unexpected Immunogenicity

Technology / Case number: #23762HJ
Darrell J Irvine / Shane Crotty
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Fabrication of Polymeric Microneedles with Hollow and Porous Tips via a Simple Micromolding Process Assisted by Ionic Salts

Technology / Case number: #24093
Benedetto Marelli / Doyoon Kim
Technology Areas: Agriculture & Food / Chemicals & Materials
Impact Areas: Advanced Materials
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A Machine Learning-guided Whole-Organ Optical Imaging Technique for Non-destructive Identification of Early Pre-Cancer Lesions and Harvesting of Viable Cells from the same for Organoid Culture

Technology / Case number: #25480
Angela Belcher / Vivek Rastogi / Neelkanth Manoj Bardhan
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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Minimally Invasive Electroceutical Catheters

Technology / Case number: #22483J
Ellen Roche / Manisha Singh / Terry Steele
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Augmentation of T and B Cell Activation with a Novel Cysteine Protease Linker Sequence

Technology / Case number: #25338
Tyler Jacks / Sean-Luc Shanahan
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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An Ingestible Stackable Gastric Resident System for Gastrointestinal Applications

Technology / Case number: #25424J
Robert Langer / Matt Murphy / SeungHo Lee / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems
Impact Areas: Healthy Living
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Core-shell Nanodisc Synthesis and Applications to Single-Particle Targeted Magnetothermal Control of Biological Signaling

Technology / Case number: #24461
Polina Anikeeva / Florian Koehler / Ye Ji Kim
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Double Core-shell Nanodisc Synthesis and Application to Magnetoelectric Bio-signaling

Technology / Case number: #24486
Polina Anikeeva / Florian Koehler / Ye Ji Kim
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Ultrafast Single-Step High-Density Conjugation of Quantum Dots and Rods with 2D Lattice Templated Array Alignment using DNA Origami

Technology / Case number: #24671
Mark Bathe / Xin Luo / Chi Chen / Rob Macfarlane
Technology Areas: Chemicals & Materials / Electronics & Photonics
Impact Areas: Advanced Materials
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Dynamic Control of a Fiber Manufacturing Process using Deep Reinforcement Learning

Technology / Case number: #22652
Brian Anthony / Sangwoon Kim / Donghyun Kim
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Industrial Engineering & Automation
Impact Areas: Connected World
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Fusion Capsid Therapy for COVID-19 and Applies to Other Viruses: Universal "Dominant" Antiviral to Prevent Virus Evolution and Future Pandemics (DNA/RNA/Protein)

Technology, Tangible Property / Case number: #22801MH
Robert Langer / Bowen Li / Yong Qian / Alexi Choueiri / Edward Stuart Boyden / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Molecular Imaging with LisNRs, A Novel Class of Liposome-based Contrast Agents Based on Modulation of Membrane Water Permeability

Technology / Case number: #23006
Alan Pradip Jasanoff / Jacob Simon
Technology Areas: Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Nanostructure Growth at Low Temperatures via Na-comprised Compounds

Technology / Case number: #18481
Brian L Wardle / Erica Freire Antunes / Andrew Liotta / Richard Li
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Precision and Digital Flexo-Printing Using Electrostatic Nanoporous Stamp

Technology / Case number: #18320
Anastasios John Hart / Sanha Kim
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Vertically-Aligned Insulator Nanomaterial as Structural Separator for Multifunctional Composite Energy Storage

Technology / Case number: #19840
Brian L Wardle / Yue Zhou / Luiz Henrique Acauan
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Tiny Nanoparticles for Magnetic Resonance Imaging Applications

Technology / Case number: #18105
Moungi G Bawendi / Eric Hansen / Oliver Bruns / He Wei
Technology Areas: Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Interfacial Bioconjugation on Emulsion Droplets

Technology / Case number: #20314
Timothy Manning Swager / Qifan Zhang
Technology Areas: Chemicals & Materials / Drug Delivery / Sensing & Imaging
Impact Areas: Advanced Materials
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Complex Liquid Crystal Droplets

Technology / Case number: #21760
Timothy Manning Swager / Alberto Concellon Allueva / Cassandra Zentner
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Chemiresistive Sensors Based on Carbon Nanotubes and Transition Metal Complexes

Technology / Case number: #20300
Timothy Manning Swager / Sibo Lin
Technology Areas: Chemicals & Materials / Communication Systems / Sensing & Imaging
Impact Areas: Connected World, Advanced Materials
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Macroscopic Superlubricity Using Crumpled Graphene Nanoballs

Technology / Case number: #20266
Ian Hunter / Pan Wang / Gee Hoon Park / Intak Jeon / Timothy Manning Swager
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Sustainable Future, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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