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Immunotherapeutic Approaches Directed at MZB1 for Plasma Cell and B Cell Malignancies

Technology / Case number: #26513J
Jianzhu Chen / Mariateresa Fulciniti / Mehmet Samur / Elena Maroto Martin / Yingjie Zhao / Nikola Ivica / Mikhil Munshi
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Autonomous Control and Discovery in Experiment

Technology / Case number: #26521
Dirk R Englund / Ian Berkman / Marc Bacvanski / Yong Hu
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Connected World
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Strategy to Improve Genotoxic Chemotherapy using the Rev1 C-Terminal Domain

Technology / Case number: #26149
Graham Walker / Charley Gruber / Kevin Bian / Michael Hemann
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Simple Watermark for Language Model

Technology / Case number: #25701
Elchanan Mossel
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML)
Impact Areas: Connected World
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Artificial Intelligence Training Core with Coincidence Counting Unit

Technology / Case number: #25350
Jeehwan Kim / Giho Lee
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Connected World
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Bridging Design Gaps: A Parametric Data Completion Approach With Graph-Guided Diffusion Models

Technology / Case number: #25903J
Nikos Arechiga / Matt Klenk / Frank Permenter / Chenyang Yuan / Rui Zhou / Yanxia Zhang / Faez Ahmed
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Connected World
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Systems and Methods for Generating an Object Design Using a Model with Multi-Modal Inputs

Technology / Case number: #26439J
Nikos Arechiga / Matt Klenk / Frank Permenter / Chenyang Yuan / Rui Zhou / Yanxia Zhang / Faez Ahmed
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Industrial Engineering & Automation
Impact Areas: Connected World
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Rational Mutants of Bxb1 Derived from Structural Insights

Technology / Case number: #25675J
Omar Abudayyeh / Teppei Soma / Masahiro Hiraizumi / Christopher Fell / Hiroshi Nishimasu / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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L-SOMA: Oral Delivery of a Biologic Molecule to the Stomach Wall via a Liquid Injection

Technology / Case number: #21194QJ
Robert Langer / Andreas Vegge / Jorrit Jeroen Water / Xiaoya Lu / Mikkel Wennemoes Hvitfeld Ley / Brian Jensen / Mette Poulsen / Jesper Windum / Brian Mouridsen / Mikkel Oliver Jespersen / Morten Frederiksen / Alex Abramson / Giovanni Traverso
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Peptide-Polyanion Conjugate to Activate STING Innate Immune Signaling

Technology / Case number: #26286
Paula Hammond / Justin Kaskow
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Engineered Binding Proteins that Specifically Target Bacteria

Technology / Case number: #22368
Hadley Sikes / Yining Hao / Ki-Joo Sung
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Collapsible Library Design to Enable Characterization of Hyperdiverse Peptide Libraries

Technology / Case number: #26377J
Bradley L. Pentelute / Dimuthu Vithanage / Corey Johnson / John Albin / Gha Young Lee / Wayne Vuong
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Robust Multi-Modal Tactile Sensor for Contact-Rich Manipulation Using Tactile-Diffusion Policies

Technology / Case number: #26475J
Edward Adelson / Naveen Kuppuswamy / Alan Zhao / Benjamin Burchfiel / Siyuan Feng / Russell Louis Tedrake
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Connected World
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Machine Learned Chemical Intuition for the AI Generation of Molecules within Specific Chemical Spaces

Technology / Case number: #26403
Brett McGuire / Zachary Fried
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Method for Hierarchical Time Series Reconciliation via Learning the Optimal Projection

Technology / Case number: #26179J
Georgia Perakis / Wei Sun / Asterios Tsiourvas / Yada Zhu / Pin-Yu Chen
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Sensing & Imaging
Impact Areas: Connected World
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Poly(-amino ester) Microparticles for Micronutrient Fortification

Technology / Case number: #22992
Robert Langer / Linzixuan Rhoda Zhang / Ruiqing Xiao / Ana Jaklenec
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Single Camera View-Point Shift

Technology / Case number: #26123
Jae S Lim / Julius Tao / Chong Lee
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Sensing & Imaging
Impact Areas: Connected World
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Automated Flow Synthesis of Combinatorial Protein Libraries

Technology / Case number: #26382J
Bradley L. Pentelute / Dimuthu Vithanage / Corey Johnson / John Albin / Gha Young Lee / Wayne Vuong
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Optical Neural Network Accelerator for Deep Learning

Technology / Case number: #26433J
Dirk R Englund / Chao Luan / Ryan Hamerly
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Electronics & Photonics
Impact Areas: Connected World
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Optical Ising Machine and Optical Convolutional Neural Networks

Technology / Case number: #19700
Marin Soljacic / Hengameh Bagherianlemraski / Charles Roques-Carmes / Li Jing / Tena Dubcek Varga / Yichen Shen / Scott Skirlo
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Sensing & Imaging
Impact Areas: Connected World
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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