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Split Intein-based Selection for Modified Peptide Binders to SARS-CoV-2 Spike Protein

Technology / Case number: #22502
Christopher Voigt / Andrew King / Emerson Glassey
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Multicellular Integrated Brain Tissue for Investigation and Therapeutic Discovery in Neurological Diseases

Technology / Case number: #22618P
Robert Langer / Adele Bubnys / Alice Stanton / Joel Blanchard / Li-Huei Tsai
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Dynamic Control of a Fiber Manufacturing Process using Deep Reinforcement Learning

Technology / Case number: #22652
Brian Anthony / Sangwoon Kim / Donghyun Kim
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Industrial Engineering & Automation
Impact Areas: Connected World
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Perfusable Host Microfluidic Endothelial Networks for Spheroid and Organoid Co-culture and Immune Cell Infiltration Studies

Technology / Case number: #22749
Roger Kamm / Sharon Lee / Huu Tuan Nguyen
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Tunable Phosphorylation-based Feedback Controller of Mammalian Gene Expression

Technology / Case number: #22932
Ron Weiss / Yili Qian / Domitilla Del Vecchio / Ross Jones
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Fluidic Platform for Perfusable Vascularized Tumor Spheroids and Organoids

Technology / Case number: #22942
Roger Kamm / Shun Zhang / Zhengpeng (Jason) Wan
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Lectin Fingerprinting for Mapping Viral Glycosylation and Identifying Neutralizing Antibodies

Technology / Case number: #22955
Laura L Kiessling / Amanda Dugan / Michael Wuo
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Identification of Genes and Mutations that Underlie Adaptation of Gut Microbes to Denovo Degradation of Oxalate

Technology / Case number: #23007
Jeff Gore / Avihu Yona
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Redox-Electrodes for Electrochemically-Controlled Bio-Macromolecule Interaction: Bio-Separations, Heterogeneous Enzyme Immobilization, Protein Purification and Sensing, Among Others

Technology / Case number: #18540
T. Alan Hatton / Xiao Su
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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TRAV-005 (Needles) 62/795,857

Technology / Case number: #22144J
Scott Manalis / David Weinstock / Robert Kimmerling / Selim Olcum
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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All-Optical Holographic Implementation of Constant-Depth Quantum Circuits

Technology / Case number: #21655
Dirk R Englund / Donggyu Kim
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Sensing & Imaging
Impact Areas: Uncharted Frontiers, Advanced Materials
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Machine Learning for Accelerated IBFD Tuning

Technology / Case number: #22007L
Ken Kolodziej / Aidan Cookson / Bradley Perry
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science
Impact Areas: Connected World, Advanced Materials
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Certified Control

Technology / Case number: #21653
Daniel Jackson / Xin Zhang / Nikos Gonzalez / Mike Wang / FengPing Angela Leong / Dimitris Koutentakis / Jonathan DeCastro / Soonho Kong
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Industrial Engineering & Automation
Impact Areas: Sustainable Future, Connected World
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Rapid Droplet-Based Systems for Antibody Drug Discovery

Technology / Case number: #23890J
Brandon DeKosky / Shuyan Jin / Nicoleen Boyle / Ahmed Fahad / Cheng-yu Chung / Matias Gutierrez Gonzalez
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Joint Qubit Manipulation and Readout for Majorana-Based Quantum Information Processing

Technology / Case number: #20208
Liang Fu / Constantin Schrade
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Computer Science / Electronics & Photonics
Impact Areas: Uncharted Frontiers, Advanced Materials
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High-throughput Electroporation Device

Technology / Case number: #21871
Cullen R. Buie / Sijie Chen / Po-Hsun Huang
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Brain-Computer Interface for User's Visual Focus Detection

Technology / Case number: #20246
Sanjay Emani Sarma / Alexandre Armengol Urpi
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology
Impact Areas: Healthy Living, Uncharted Frontiers, Connected World
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Distributed Training and Management of Al Powered Robots using Teleoperation via Virtual Spaces

Technology / Case number: #20397
Daniela Rus / Changhyun Choi / Aidan Fay / Jeffrey Lipton
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Industrial Engineering & Automation
Impact Areas: Uncharted Frontiers, Connected World
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Single Cell Super-Resolution Proteomics

Technology / Case number: #24088
Mark Harnett / Dimitra Vardalaki
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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Composition and Methods to Generate Assymetric Bispecific Antibodies from a Single Cell Line

Technology / Case number: #17698
Ram Sasisekharan / Andrew Hatas / Eduardo Fleischer / Vidya Subramanian / Kannan Tharakaraman
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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