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Synergisms between Small Molecule Boosters and LNP Formulations Uncovered using High Throughput Screening and Machine Learning

Technology / Case number: #26199J
Giovanni Traverso / Deepak Subramanian / Rajib Dey / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Endotoxin-Free Phage Production for Clinical Applications and Food Safety

Technology / Case number: #26012
Angela Belcher / Jack Rudrum / Mirielle Griffin / Valeria Marquez Pellegrin / Celestine Jia Huey Hong / Yanpu He
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Flow Cytometry with Mass Sensitive Readout

Technology / Case number: #12273J
Scott Manalis
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Programmable Gene Insertion with Trans-Templates

Technology / Case number: #24105
Omar Abudayyeh / Kaiyi Jiang / Jonathan S. Gootenberg
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Single-Walled Carbon Nanotube-Based Optical Sensors for Detection and Identification of Nitroaryl Environmental Toxins Explosives

Technology / Case number: #13664
Michael S. Strano
Technology Areas: Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Biodegradable Lipid-Like Materials for Applications in siRNA Delivery

Technology / Case number: #15420
Robert Langer / Joseph Dorkin / Yunlong Zhang / Arturo Vegas / Kathryn Whitehead / Daniel Anderson
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Raman Spectroscopy Based Sensitive and Specific Detection of Alternate Glycemic Markers, Glycated Hemoglobin (HbA1c) and Glycated Albumin for Longterm Diabetes Monitoring

Technology / Case number: #15295
Ramachandra Dasari / Jeon Woong Kang / Narahara Dingari / Ishan Barman
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Primary and Secondary Biodegradable Batteries as Power Sources for Bioelectronics

Technology / Case number: #26190J
Giovanni Traverso / Mehmet G Say
Technology Areas: Biotechnology / Energy & Distribution
Impact Areas: Advanced Materials
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Activity-Based Nanosensors of Lung Cancer

Technology / Case number: #20311H
Sangeeta Bhatia / Jesse Kirkpatrick / Jaideep Dudani / Colin Buss / Andrew Warren
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Programmable Insertion Approaches Via Reverse Transcriptase Recruitment

Technology / Case number: #23685
Omar Abudayyeh / Kaiyi Jiang / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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System for Accelerating Parallel Magnetic Resonance Imaging Reconstruction Using Joint Estimation with a Sparse Signal Model

Technology / Case number: #15457J
Vivek Goyal / Leo Grady / Daniel Weller / Lawrence Wald
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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1,3,5-triazinane-2,4,6-trione (TNT) Derivatives and Uses Thereof

Technology / Case number: #15446
Robert Langer / Hao Yin / Akinleye Alabi / Joseph Dorkin / Ahmed Eltoukhy / Yizhou Dong / Delai Chen / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Dynamic Nuclear Polarization with Rigid Biradicals

Technology / Case number: #13595JQ
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Heterocycle-Modified Quinolines for Fluorescence-Based Protein Kinase Sensing

Technology / Case number: #13876
Barbara Imperiali
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Wearable Full-Body Motion Tracking System with Detailed Hand Tracking by Ultrasound Wristbands

Technology / Case number: #26219
Xuanhe Zhao / Gengxi Lu
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Compositions and Methods to Deliver RNA to Extracellular Matrix Producing Cells

Technology / Case number: #25390J
Daniel Anderson / Dennis Shi / Theresa Raimondo / Sho Toyonaga
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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A Novel Multiplexed Inertial Focusing Microfiltration System for Intra-Operative Blood Salvage Autotransfusion

Technology / Case number: #17212DJE
Jongyoon Han / Kah Ping Andy Tay / Majid Ebrahimi Warkiani / Lidan Wu / Guofeng Guan / Chwee-Teck Lim
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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An Approach for Enriching the Production of DNA Cargo Loaded AAV5 Capsids in Cells

Technology / Case number: #25585
Anthony Sinskey / John Joseph / Prasanna Srinivasan / Jacqueline Wolfrum / Rui Wen Ou / Stacy Springs / Richard D Braatz / Paul Barone
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Reversible and Ratiometric Sensing using Nanocrystals

Technology / Case number: #11693
Moungi G Bawendi / Daniel Nocera
Technology Areas: Biotechnology / Diagnostics / Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Methods for the Production of Porous Scaffolds Comprising Multiple Layers with Distinct Characteristics

Technology / Case number: #11730QJ
Ioannis Yannas
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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