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A Fabrication-Free Microfluidic Device for Scalable, High-Volume Bacterial Electroporation

Technology / Case number: #23552
Cullen R. Buie / Sijie Chen / Po-Hsun Huang
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Nucleic Acid-Conjugated Polymeric Nanoparticles for Gene Therapy

Technology / Case number: #23628JQ
Natalie Artzi / Alexander M Cryer / Pere Dosta Pons
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Engineered Alum-binding SARS-CoV-2 Immunogens

Technology / Case number: #23632H
Darrell J Irvine / Kristen Rodrigues / Sergio Rodriguez / Neil Dalvie / J. Christopher Love
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Peptide-Encoded Libraries of Small Molecules for De Novo Drug Discovery

Technology / Case number: #23712
Stephen Buchwald / Simon Roessler / Nathalie Grob / Bradley L. Pentelute
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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High-Throughput and High-Precision Measurement of Single-Cell Density

Technology / Case number: #23740
Scott Manalis / Teemu Miettinen / Weida Wu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Intracellular Molecular Recording and Memory via Protein Self-Assembly

Technology / Case number: #23746HPM
Edward Stuart Boyden / Changyang Linghu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Activity-based Cell Sorting

Technology / Case number: #23765HJ
Sangeeta Bhatia / Ava Soleimany / Jesse Kirkpatrick
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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DNA-Dye Assembly Based Single-Molecule Fluorescence Lifetime Imaging Probes

Technology / Case number: #23780
Mark Bathe / Jiajia Guo / Gabriela Schlau-Cohen / Xiao Wang / Stephanie Hart
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Method and Apparatus for Inferring Elevated Pulmonary Capillary Wedge Pressures from Single-Lead Electrocardiogram Telemetry Data

Technology, Software / Case number: #23955J
Collin M Stultz / Eugene Pomerantsev / Ridwan Alam / Daphne Schlesinger
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Activatable Antimicrobial Peptides and Uses Thereof

Technology / Case number: #24024H
Sangeeta Bhatia / Chayanon Ngambenjawong
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Epoxides for Multimodal Detection of Biomolecules by Expansion Microscopy

Technology / Case number: #24137HM
Edward Stuart Boyden / Yi Cui
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Adhesive, Injectable Hydrogels for Local Therapy Delivery to Brain Tumors

Technology / Case number: #24170JQ
Natalie Artzi / Dahis Daniel / Michelle Dion
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Intrinsically Stretchable Microelectronic Fibers and Their Assemblies as Multifunctional Bioelectronic Interfaces for Whole Organs

Technology / Case number: #24178
Polina Anikeeva / Rajib Mondal / Atharva Sahasrabudhe
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Universal Redirection of Chimeric Antigen Receptor T Cells Against Solid Tumors via Tumor Cell Membrane-Inserting CAR Ligands

Technology / Case number: #24270H
Darrell J Irvine / Alexander Hostetler / Laura Chen / Angela Zhang
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Customized Passive Prosthetic Feet

Technology / Case number: #24341
Amos Winter / Charlotte Folinus
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Tissue-integrating Neural Interfaces

Technology / Case number: #24351
Polina Anikeeva / Anthony Tabet
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Smooth Flow Control Systems for Embedded Micropumps on Microfluidic Cell Culture Devices

Technology / Case number: #24379
Linda Griffith / Allison Lenhard / David L Trumper
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Core-shell Nanodisc Synthesis and Applications to Single-Particle Targeted Magnetothermal Control of Biological Signaling

Technology / Case number: #24461
Polina Anikeeva / Florian Koehler / Ye Ji Kim
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Double Core-shell Nanodisc Synthesis and Application to Magnetoelectric Bio-signaling

Technology / Case number: #24486
Polina Anikeeva / Florian Koehler / Ye Ji Kim
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Compositions for the Conditional Delivery of Macromolecules and Combination Therapeutics

Technology / Case number: #24492H
Sangeeta Bhatia / Qian Zhong / Edward Tan / Chayanon Ngambenjawong
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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