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Control Replication and Transcription of Self-Replicating RNA in Responses to Small Molecule TMP

Technology / Case number: #22331H
Darrell J Irvine / Parisa Yousefpour / Jan Lonzaric / Yingzhong Li / Ron Weiss
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Split Intein-based Selection for Modified Peptide Binders to SARS-CoV-2 Spike Protein

Technology / Case number: #22502
Christopher Voigt / Andrew King / Emerson Glassey
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Compositions of Polypeptides for Subunit Vaccines for SARS-CoV-2

Technology / Case number: #22703
J. Christopher Love / Sergio Rodriguez / Neil Dalvie
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Novel Peptides to Inhibit Ena/VASP Proteins

Technology / Case number: #22897J
Amy Keating / Samantha Hill / Ghassan Mouneimne / Sara Parker / Meucci IIunga / Theresa Hwang
Technology Areas: Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Lectin Fingerprinting for Mapping Viral Glycosylation and Identifying Neutralizing Antibodies

Technology / Case number: #22955
Laura L Kiessling / Amanda Dugan / Michael Wuo
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Multi-Targeted, Tunable, Sustained Delivery of Drugs and Other Payloads to Charged Avascular Tissues

Technology / Case number: #21303
Alan Grodzinsky / Yamini Krishnan
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Targeting Dendritic Cell Lectins with Glycosylated Particles Containing TLR Ligands Facilitates Efficient Immune Responses

Technology / Case number: #24570J
Laura L Kiessling / Robert Hincapie / Mohammad Murshid Alam / M.G. Finn / Valerie Lensch
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Synthetic Mucin Glycans as Antifungal Agents

Technology / Case number: #24073J
Katharina Ribbeck / Rachel Hevey / Julie Takagi
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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Synthesis of Covalent Protein Dimers that can Inhibit MYC-Driven Transcription

Technology / Case number: #23305WJ
Stephen Buchwald / Charles Li / Susana Hawken / Ann Boija / Muhammad Jbara / Jacob Rodriguez / Andrei Loas / Sebastian Pomplun / Carly Schissel / Isaac Klein / Bradley L. Pentelute
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Targeting Lung Microbiota and its Responding Immune Pathways for Lung Cancer Treatment

Technology / Case number: #20602HRJ
Tyler Jacks / Georgia Lagoudas / Chengcheng Jin / Paul Blainey
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Target for Modulating Body Mass

Technology / Case number: #21326
Jianzhu Chen / Ting Dong / Yingzhong Li / Nikola Ivica
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Composition and Methods to Generate Assymetric Bispecific Antibodies from a Single Cell Line

Technology / Case number: #17698
Ram Sasisekharan / Andrew Hatas / Eduardo Fleischer / Vidya Subramanian / Kannan Tharakaraman
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Selective Metal-Mediated Arylation of Dichalcogenides in Biomolecules

Technology / Case number: #17814
Stephen Buchwald / Daniel Cohen / Chi Zhang / Bradley L. Pentelute
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Functionalization of Protective Antigen by Chemical Conjugation

Technology / Case number: #20802
Bradley L. Pentelute / Zeyu Lu
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Platform for Continuous Directed Evolution in Human Cells

Technology / Case number: #19909
Matthew D. Shoulders / Samuel Hendel / Chet Berman / Christopher Moore / Louis Papa
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Continuous Freeze-Drying of Pharmaceuticals and Biopharmaceuticals in Unit Doses

Technology / Case number: #19494J
Bernhardt Trout / Capozzi Carlo / Roberto Pisano
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Engineered Phagemids for Non-Lytic, Targeted Antibacterial Technologies

Technology / Case number: #18186HJY
James Collins / Michael Lobritz / Prerna Bhargava / Russell-John Krom
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Novel Peptidic Agents for Targeting Chemoresistant Anti-Apoptotic Mcl-1

Technology / Case number: #18162
Amy Keating / Raheleh Rezaei Araghi
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Development of Multi-Specific Antibody-Serum Albumin Fusion Proteins Targeting Multiple Human and Murine CXC (ELR+) Chemokines

Technology / Case number: #19355JQ
Karl Dane Wittrup / Andrew Luster / Alessandro Angelini
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Discovery of Self-Labeling Miniproteins

Technology / Case number: #18742
Bradley L. Pentelute / Ethan Evans
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Uncharted Frontiers, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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