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Selective Metal-Mediated Arylation of Dichalcogenides in Biomolecules

Technology / Case number: #17814
Stephen Buchwald / Daniel Cohen / Chi Zhang / Bradley L. Pentelute
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Transcriptional Sensor for Bile Acids in Bacteroides Thetaiotaomicron

Technology / Case number: #18573
Christopher Voigt / Mao Taketani
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Platinum-Anthracycline Derivative Conjugates and Their Therapeutic Applications

Technology / Case number: #20922
Stephen J Lippard / Jonathan Braverman / Fang Wang / Omer Yilmaz
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Convergent and Biomimetic Enantioselective Total Synthesis of (-)-Communesin F

Technology / Case number: #18676
Mo Movassaghi / Wen-Tau Chang / Matthew Pompeo / Stephen Lathrop
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Intraperitoneal Injection of Nanoparticles Results in Near Perfect Localization Within Peritoneal Tumor Deposits

Technology / Case number: #19352
Angela Belcher / Zhimin Tao / Paiman Ghoroghchian / Xiangnan Dang
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Identification and Application of Ketogenic Properties of Intestinal Stem Cell

Technology / Case number: #20090
George Eng / Fang Wang / Chia-Wei Cheng / Omer Yilmaz
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Detection of Amines by Chemiresistive Sensors

Technology / Case number: #17693
Timothy Manning Swager / Graham Sazama / Sophie Liu
Technology Areas: Agriculture & Food / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living
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Small Molecule Binders of the Oncogenic Fusion Transcription Factor PAX3-FOXO1

Technology / Case number: #23850J
Angela Koehler / Marco Wachtel / Beat Schaefer / Madeleine Henley / Becky Leifer / Shelby Doyle
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Metal-Organic Frameworks Mediated Macromolecule Delivery System

Technology / Case number: #22862J
Robert Langer / Xiaoyue Qi / Adam Wentworth / Giovanni Traverso
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Novel Small Molecule Modulators of Myb-Mediated Transcription with Potential Use for Cancer Therapy

Technology / Case number: #22044
Angela Koehler / Jasmin Kruell / Brice Curtin / Florian Kabinger / Becky Leifer
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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A Platform for Continuous Directed Evolution in Human Cells

Technology / Case number: #19909
Matthew D. Shoulders / Samuel Hendel / Chet Berman / Christopher Moore / Louis Papa
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Crystal Structures of Human TorsinA and its Dystonia Mutant

Technology / Case number: #18394
Thomas Schwartz / Brian Sosa-Alvarado / Fatma Esra Demircioglu
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Compositions and Methods to Increase Muscular Strength Without Exercise

Technology / Case number: #19768
Roger Kamm / Vivek Sivathanu
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Drug Delivery Based on Bistable Membrane

Technology / Case number: #17624
Michael Cima
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Potent Agelastatin Derivatives as Modulators for Cancer Invasion and Metastasis

Technology / Case number: #19505J
Mo Movassaghi / Kun Xu / Alyssa Antropow / Rachel Buchsbaum
Technology Areas: Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Continuous Freeze-Drying of Pharmaceuticals and Biopharmaceuticals in Unit Doses

Technology / Case number: #19494J
Bernhardt Trout / Capozzi Carlo / Roberto Pisano
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Engineered Phagemids for Non-Lytic, Targeted Antibacterial Technologies

Technology / Case number: #18186HJY
James Collins / Michael Lobritz / Prerna Bhargava / Russell-John Krom
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Novel Peptidic Agents for Targeting Chemoresistant Anti-Apoptotic Mcl-1

Technology / Case number: #18162
Amy Keating / Raheleh Rezaei Araghi
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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PNA Amphiphile Adjuvant Delivery Vehicles

Technology / Case number: #18878H
Darrell J Irvine / Eric Dane
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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M13 Phage Assembly System for Optimal Blood Trafficking, Tumor Penetration, and Passage Across the Blood Brain Barrier

Technology / Case number: #19438
Angela Belcher / Fred Lam / Uyanga Tsedev
Technology Areas: Drug Delivery / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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