Novel Small Molecule Modulators of Myb-Mediated Transcription with Potential Use for Cancer Therapy
Provided herein are compounds that inhibit the function of MYB. In particular, provided are compounds that can inhibit MYB and/or disrupt the interaction between MYB and a protein associated with MYB, a protein whose dysregulation is implicated in cancer. Also provided are pharmaceutical compositions comprising the compounds, methods of inhibiting MYB function, and methods of treating cancer in a subject by administering a compound or composition described herein.
Researchers
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modulators of myb-mediated transcription and uses thereof
United States of America | Published application
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