Metal-Organic Frameworks Mediated Macromolecule Delivery System
This invention presents articles and methods for administering biomolecules to subjects using metal-organic frameworks, addressing challenges associated with oral delivery in the gastrointestinal (GI) tract. The article consists of a substrate with an adhesive layer, a support layer, and an active material containing a composite of a metal-organic framework and a biomolecule. By overcoming the harsh conditions of the GI tract, this innovation provides an improved method for treating subjects with therapeutic biomolecules, ensuring their efficacy is maintained throughout oral administration.
Researchers
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metal-organic framework mediated macromolecule delivery system
United States of America | Published application
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