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Colon Delivery Platform for Constipation Treatment

Technology / Case number: #20570JQ
Robert Langer / Christoph Winfried Johannes Steiger / Joshua Korzenik / Giovanni Traverso
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Machine Learning-Guided Discovery of Nanoparticle Formulations Maximizing mRNA Transfection

Technology / Case number: #25890J
Giovanni Traverso / Taksim Ahmed / Hao Song / Xisha Huang / Simon Qu / Deepak Subramanian / Jonathan Woo / Alvin Chan / Joshua Bernstock / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Mucin-Inspired Glycopolypeptides for Managing Microbial Infections

Technology / Case number: #26189J
Katharina Ribbeck / Jessica Kramer / Michaela Gold / Kelsey Wheeler
Technology Areas: Therapeutics
Impact Areas: Healthy Living
Labels
  • Women's Health
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A Novel Injectable Thiol-Acrylate Poly(ethylene Glycol) Hydrogel for Sustained Release of Methylprednisolone Sodium Succinate

Technology / Case number: #14439J
Robert Langer / Jonathan Slotkin / Francis Reynolds / Timothy O'Shea / Daniel Siegwart / Christopher Pritchard / Eric Woodard / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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CD80 is a Biomarker of p53 Activity and a Target for Cancer Therapy

Technology / Case number: #15386H
Tyler Jacks / Leah Schmidt / David Feldser
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Polyamine-Fatty Acid Derived Lipidoids for Drug Delivery

Technology / Case number: #16367
Daniel Anderson / Rebecca McClellan / Owen Fenton / Joseph Dorkin
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Valency Controlled Quantum Dots with Tunable Number of Biotin Binding Sites

Technology / Case number: #12606B
Moungi G Bawendi / Alice Ting
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living
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Methods and Compositions for Protein Labeling Using Lipoic Acid Ligases

Technology / Case number: #12773
Alice Ting
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
License

Self-Assembling Peptides Incorporating Modifications and Methods of Use Thereof

Technology / Case number: #13846XE
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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A Mitochondria Targeting Platinum(IV) Complex with Dual Cell Killing Modes

Technology / Case number: #13271
Stephen J Lippard
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Formulation of Polymeric Particles for Prostate Cancer Targeting

Technology / Case number: #12162J
Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Antigenically Intact Hemagglutinin in Circulating Avian and Swine Influenza Viruses and Potential for H3N2 Pandemic

Technology / Case number: #16225
Rahul Raman / Kannan Tharakaraman / Ram Sasisekharan
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Immune Pharmacytes: Nanoparticle-Modified Leukocytes for Immunotherapy

Technology / Case number: #13509H
Darrell J Irvine
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Engineered Probiotics for Urinary Cancer Diagnosis

Technology / Case number: #15881HJ
Sangeeta Bhatia / Jeff Hasty / Arthur Prindle / Tal Danino
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Methods for Treating Polycystic Kidney Disease

Technology / Case number: #16389J
John M Essigmann / Stefan Somlo / Sorin Fedeles / Bogdan I Fedeles / Robert Croy
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Single Wall Carbon Nanotubes as In Vivo Sensors

Technology / Case number: #16531
Michael S. Strano / Nicole Iverson / Thomas McNicholas / Nigel Reuel
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Diminished Proteolytic Shedding of Receptor Tyrosine Kinases Mediates MEK Inhibitor Resistance in Triple-Negative Breast Cancer

Technology / Case number: #16742
Linda Griffith / Madeleine Oudin / Miles Miller / Aaron Meyer / Frank Gertler / Douglas Lauffenburger
Technology Areas: Therapeutics
Impact Areas: Healthy Living
Labels
  • Women's Health
License

High Throughput Isolation of Antigen-Specific Antibodies and Cells

Technology / Case number: #16927J
Jongyoon Han / Galit Alter / Aniruddh Sarkar / Han Wei Hou
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Salmochelin-Antibiotic Conjugates for Targeting Gram-Negative Pathogens

Technology / Case number: #16939
Elizabeth M. Nolan / Phoom Chairatana / Tengfei Zheng
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Siderophore-Based Immunization Against Gram-Negative Bacteria

Technology / Case number: #16976J
Elizabeth M. Nolan / Araceli Perez-Lopez / Martina Corsi / Manuela Raffatellu / Phoom Chairatana
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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