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Programmable Addition Via Site-Specific Targeting Elements (PASTE)

Technology / Case number: #22225
Omar Abudayyeh / Jonathan S. Gootenberg
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Discovery and Engineering of Novel Integrases for High-Efficiency Gene Integration

Technology / Case number: #23554
Omar Abudayyeh / Justin Lim / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Flow Cytometry with Mass Sensitive Readout

Technology / Case number: #12273J
Scott Manalis / Ken Babcock / Michel Godin / Thomas Burg
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Programmable Gene Insertion with Trans-Templates

Technology / Case number: #24105
Omar Abudayyeh / Kaiyi Jiang / Jonathan S. Gootenberg
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Single-Walled Carbon Nanotube-Based Optical Sensors for Detection and Identification of Nitroaryl Environmental Toxins Explosives

Technology / Case number: #13664
Michael S. Strano / Jingqing Zhang / Daniel Heller / George Pratt
Technology Areas: Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Raman Spectroscopy Based Sensitive and Specific Detection of Alternate Glycemic Markers, Glycated Hemoglobin (HbA1c) and Glycated Albumin for Longterm Diabetes Monitoring

Technology / Case number: #15295
Ramachandra Dasari / Jeon Woong Kang / Narahara Dingari / Ishan Barman
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Activity-Based Nanosensors of Lung Cancer

Technology / Case number: #20311H
Sangeeta Bhatia / Jesse Kirkpatrick / Jaideep Dudani / Colin Buss / Andrew Warren
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Programmable Insertion Approaches Via Reverse Transcriptase Recruitment

Technology / Case number: #23685
Omar Abudayyeh / Kaiyi Jiang / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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System for Accelerating Parallel Magnetic Resonance Imaging Reconstruction Using Joint Estimation with a Sparse Signal Model

Technology / Case number: #15457J
Vivek Goyal / Leo Grady / Daniel Weller / Lawrence Wald
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
License

1,3,5-triazinane-2,4,6-trione (TNT) Derivatives and Uses Thereof

Technology / Case number: #15446
Robert Langer / Hao Yin / Akinleye Alabi / Joseph Dorkin / Ahmed Eltoukhy / Yizhou Dong / Delai Chen / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Fully-synthetic Extracellular Microenvironments for in Vitro Stem Cell Propagation and Organogenesis

Non-Exclusively Licensed Technology / Case number: #20047
Linda Griffith / Victor Hernandez-Gordillo
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Dynamic Nuclear Polarization with Rigid Biradicals

Technology / Case number: #13595JQ
Robert Guy Griffin / Francois Le Moigne / Hakim Karoui / Olivier Ouari / Thorsten Maly / Yoh Matsuki / Paul Tordo
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
License

Heterocycle-Modified Quinolines for Fluorescence-Based Protein Kinase Sensing

Technology / Case number: #13876
Barbara Imperiali / Juan Gonzalez Vera / Elvedin Lukovic
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
License

A Novel Injectable Thiol-Acrylate Poly(ethylene Glycol) Hydrogel for Sustained Release of Methylprednisolone Sodium Succinate

Technology / Case number: #14439J
Robert Langer / Jonathan Slotkin / Francis Reynolds / Timothy O'Shea / Daniel Siegwart / Christopher Pritchard / Eric Woodard / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Methods for Microbial Oil Overproduction via Amplification of the Biosynthetic and Sequestration Pathways Individually or in Combination

Technology / Case number: #15152
Gregory Stephanopoulos / Sagar Chakraborty / Mitchell Tai
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

A Novel Multiplexed Inertial Focusing Microfiltration System for Intra-Operative Blood Salvage Autotransfusion

Technology / Case number: #17212DJE
Jongyoon Han / Kah Ping Andy Tay / Majid Ebrahimi Warkiani / Lidan Wu / Guofeng Guan / Chwee-Teck Lim
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Distinct Gene Systems Mediating Activity-Dependent Plasticity in Visual Cortex

Technology / Case number: #11841P
Mriganka Sur / Gabriel Kreiman / Daniela Tropea / Shayan Mukherjee / Alvin Lyckman
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Intraoperative Coded Aperture Radioscintigraphic Imaging of Cancer

Technology, Software / Case number: #11901J
Richard Lanza / John Idoine / John Frangioni / Roberto Accorsi
Technology Areas: Biotechnology / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
License

Oscillating Cell Culture Bioreactor

Technology / Case number: #12301
Lisa Freed / Matteo Moretti / Robert Langer
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Glucose Valve and Other Metabolite Valves

Technology / Case number: #12369
Tae Moon / Kevin Solomon / Kristala L Jones Prather
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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