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The Design of DNA-scaffolded Subunit Vaccines for Enhanced Germinal Center Responses in HIV Vaccination

Technology / Case number: #25982H
Darrell J Irvine / Anna Romanov / Grant Knappe / Mark Bathe
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Advanced Materials
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Ligand-Inducible Post-Transcriptional Gene Regulation Using Protein-Binding RNA Aptamers

Technology / Case number: #13998J
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Tissue Specific Delivery of Interfering RNA

Technology / Case number: #13947H
Sangeeta Bhatia
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Peptide Nucleic Acid Functionalized Hydrogel Microneedles for Sampling and Detection of Interstitial Fluid Nucleic Acids

Technology / Case number: #21359HJ
Darrell J Irvine / Dana Al Sulaiman / Sylvain Ladame / Yin Hao Chang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Development of a Platform to Noninvasively Image Car T Cells

Technology / Case number: #25905J
Michael Hemann / Julia Froese / Ali Salehi / Taha Rakhshandehroo / Jennifer Rowley / Mohammad Rashidian
Technology Areas: Biotechnology / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Full-field Optical Coherence Microscopy System Using a Digital Focal Plane Array

Technology / Case number: #24144LJ
Guillermo Tearney / Michael Bradshaw / Osman Ahsen / Matthew Johnson / Joseph Gardecki
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Advanced Materials
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Fast Nonlinear Dynamic Electrochemical Characterization of Arbitrary Fluids

Technology / Case number: #24656
Ian Hunter / Billal Iqbal / Kimberley Cheng / Michael Aling
Technology Areas: Agriculture & Food / Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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One-Step Construction of Allogeneic CAR-NK Cells with Increased Anti-Tumor Cytotoxicity and Resistant to Rejection by Host T Cells and NK Cells

Technology / Case number: #25757J
Jianzhu Chen / Fuguo Liu / Rizwan Romee
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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RNA Degradation-based Toggle Switch

Technology / Case number: #21622
Ron Weiss / Noreen Wauford / Breanna DiAndreth
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Anti-Ebola Neutralizing Antibodies

Technology / Case number: #17334
Ram Sasisekharan / Devin Quinlan / Vidya Subramanian / Kannan Tharakaraman
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Boron-Containing Pharmacophore

Technology / Case number: #21111
Ronald T Raines / Brian Graham / Ian Windsor
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods of Breeding, Maintaining, and Releasing Wild-Like Organisms with Desired Genetics

Technology / Case number: #20965TEJ
Kevin Esvelt / Sam Telford III
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Sustainable Future
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Single-Step Insertion into Repeated Regions for Efficient Multi-Locus Assortment and Daisyfield Drive

Technology / Case number: #19136TJE
Kevin Esvelt / Charleston Noble / Jianghong Min
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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Novel Short Tandem Repeats (STRs) Analysis Methods

Technology / Case number: #18500L
James Harper / James Watkins / Philip Fremont-Smith / Adam Michaleas / Joseph Isaacson / Darrell Ricke / Brian Helfer / Anna Shcherbina / Edward Wack / Eric Schwoebel / Martha Petrovick
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Synthetic Hydrogels for Stem Cell Propagation and Organogenesis

Technology / Case number: #20047
Linda Griffith
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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  • Women's Health
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DIAL: Programmable Promoter Editing to Generate Defined, Heritable Setpoints of Gene Expression

Technology / Case number: #25874
Katie Galloway / Mary Ehmann / Yunbeen Bae / Sneha Kabaria
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Peptide-Targeted Layer-by-Layer Nanoparticle for Glioblastoma Treatment

Technology / Case number: #25659
Paula Hammond / Priya Ganesh / Andrew Pickering / Nicholas Lamson / Natalie Boehnke
Technology Areas: Chemicals & Materials / Drug Delivery / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Implantable piezoelectric ultrasound stimulator (ImPULS)

Technology / Case number: #25217TE
Canan Dagdeviren / Md Osman Goni Nayeem / Jason Hou
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Enhanced Differentiation to Endodermal Derivatives with Modulated Oxygen Level

Technology / Case number: #15589
Clark Colton / Amanda Diienno / Jeffrey Millman
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Two Person Mixture Deconvolution for Application with ForenSeq Kintelligence Workflow

Technology / Case number: #24078L
Philip Fremont-Smith / Natalie Damaso / Chelsea Lennartz
Technology Areas: Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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