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3D Knit Spacesuit Sleeve with Multifunctional Fibers and Tunable Compression

Technology / Case number: #24607
Hugh M Herr / Christopher Shallal / Cody Paige / Rachel Bellisle / Jesus Guillermo Herrera Arcos / Ganit Goldstein / Atharva Sahasrabudhe / Volodymyr Korolovych / Lavender Tessmer / Svetlana V Boriskina / Skylar Tibbits / Dava Newman
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Uncharted Frontiers, Advanced Materials
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Library-Scale Methods for Antibody Functional Screening

Technology / Case number: #24645
Brandon DeKosky
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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In Solution Monoclonal Polony Generation on Inorganic Nanoparticle

Technology / Case number: #25039
Ashwin Gopinath / Emily Wu / Nayan Agarwal
Technology Areas: Chemicals & Materials / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Advanced Materials
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Circular, Strained Zymogen

Technology / Case number: #21110J
Ronald T Raines / Ian Windsor
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Chimeric Antigen Receptor Signaling Domains Derived via Activity-based Directed Evolution

Technology / Case number: #21116
Michael Birnbaum / Taeyoon Kyung
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Optimization of Circular Single Stranded DNA using M13 Phage

Technology / Case number: #21211
Angela Belcher / Tae-Gon Cha / Uyanga Tsedev / Christopher Voigt
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Characterization and Utilization of a Subgenomic Promoter Mutant Library for Tuning Expression of Multiple Transgenes from Alphavirus Replicons

Technology / Case number: #21309
Ron Weiss / Jin Huh
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Endogenous Gene Sensing and Actuation by Placement of Non-Coding RNA after Transcriptional Termination Signals

Technology / Case number: #21520
James Collins / Casper Enghuus / Elvira Vitu / Jeremy Gam / Ron Weiss
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Anti-Human KLRB1 Monoclonal Antibodies and Uses Thereof

Technology / Case number: #21645J
Karl Dane Wittrup / Nathan Mathewson / Byong Ha Kang / Kai Wucherpfennig
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Systems and Assays for Identifying PU.1 Inhibitors

Technology / Case number: #21734P
Li-Huei Tsai / Alison Mungenast / William Ralvenius
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Dynamic Soft Robotic Heart Model Combining Biohybrid Materials

Technology / Case number: #22057J
Xuanhe Zhao / Christopher Nguyen / Clara Park / Ellen Roche / Hyunwoo Yuk
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living, Advanced Materials
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TRAV-007 (Genome Sequencing) 62/790,799

Technology / Case number: #22143J
Scott Manalis / Keith Ligon / Mark Stevens / Robert Kimmerling
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Centrifugal Microfluidic Platforms for Cell Pairing and Fusion

Technology / Case number: #22275J
Joel Voldman / Sergio Martinez-Chap / Sergio Martínez-Chapa / MohammadMahdi Aeinhvand
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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High-Throughput Expansion Microscopy

Technology / Case number: #22339
Laurie Boyer / Catherine Della Santina / John Day / Alexander Auld / Pema Maretich / Edward Stuart Boyden
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Split Intein-based Selection for Modified Peptide Binders to SARS-CoV-2 Spike Protein

Technology / Case number: #22502
Christopher Voigt / Andrew King / Emerson Glassey
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Multicellular Integrated Brain Tissue for Investigation and Therapeutic Discovery in Neurological Diseases

Technology / Case number: #22618P
Robert Langer / Adele Bubnys / Alice Stanton / Joel Blanchard / Li-Huei Tsai
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Dynamic Control of a Fiber Manufacturing Process using Deep Reinforcement Learning

Technology / Case number: #22652
Brian Anthony / Sangwoon Kim / Donghyun Kim
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Industrial Engineering & Automation
Impact Areas: Connected World
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Perfusable Host Microfluidic Endothelial Networks for Spheroid and Organoid Co-culture and Immune Cell Infiltration Studies

Technology / Case number: #22749
Roger Kamm / Sharon Lee / Huu Tuan Nguyen
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Tunable Phosphorylation-based Feedback Controller of Mammalian Gene Expression

Technology / Case number: #22932
Ron Weiss / Yili Qian / Domitilla Del Vecchio / Ross Jones
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Fluidic Platform for Perfusable Vascularized Tumor Spheroids and Organoids

Technology / Case number: #22942
Roger Kamm / Shun Zhang / Zhengpeng (Jason) Wan
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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