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Ionizable Lipid OF-02 and its Use in mRNA Delivery

Technology / Case number: #17733
Daniel Anderson / Rebecca McClellan / Kevin Kauffman / Owen Fenton / Joseph Dorkin
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Electron Conducting Carbon-Based Cement (e-C3)

Technology / Case number: #20148J
Franz-Josef Ulm / Renal Backov / Thibaut Louis Alexandre Divoux / Nicolas Chanut / Aikaterini Ioannidou / Roland Pellenq
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future
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Visible Light-Driven CO2 Capture and Release Using Photoactive Pyranine in Water in Continuous Flow

Technology / Case number: #25603
T. Alan Hatton / Johannes Schretter / Hyowon Seo
Technology Areas: Communication Systems / Environmental Engineering / Sensing & Imaging
Impact Areas: Climate Stabilization, Sustainable Future
Labels
  • CO2 Capture
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Use of Organic Cations for Selective Electrochemical CO2 Conversions to Methanol

Technology / Case number: #25749
Yang Shao-Horn / Davide Menga
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future
Labels
  • CO2 Capture
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Human Microbiome Clostridia-Derived Biosynthetic Enzymes/Pathways for the Biological Production of Natural and Non-Natural Fatty Acylated Compounds

Technology / Case number: #20961
Christopher Voigt / Fang-Yuan Chang
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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In Vitro and in Vivo Delivery of Complex Genetic Circuits up to 33kb Using Engineered HSV-1

Technology / Case number: #20746
Ron Weiss / Ross Jones / Jin Huh / Maria Hottelet Foley
Technology Areas: Diagnostics / Drug Delivery
Impact Areas: Healthy Living
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Oligomeric Conjugates for siRNA Delivery and Glucose-Responsive Insulins

Technology / Case number: #15977J
Robert Langer / Rosemary Kanasty / Arturo Vegas / Daniel Anderson
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Lipids and Formulations for Intramuscular and Systemic Delivery of mRNA

Technology / Case number: #25351J
Daniel Anderson / Kaelan Reed / Akash Gupta / Arnab Rudra
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Layer-by-Layer Based Nanoparticles for Systemic Delivery Applications

Technology / Case number: #14680
Paula Hammond / Zhiyong Poon
Technology Areas: Chemicals & Materials / Computer Science / Drug Delivery
Impact Areas: Healthy Living
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Bioprocess and Microbe Engineering for Total Carbon Utilization in Biofuel Production

Technology / Case number: #14119
Gregory Stephanopoulos
Technology Areas: Environmental Engineering
Impact Areas: Climate Stabilization
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Tunable Structure of Biodegradable Silk-Based Microcapsules for Soluble and Insoluble Payload Delivery

Technology / Case number: #23764J
Benedetto Marelli / Yagmur Yegin / Bernd Oschmann / Rupert Konradi / Ophelie Zeyons / Henning Urch / Pierre-Eric Millard / Muchun Liu
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Electrochemical Oxygen Compression Combined Cycle (EOC3)

Technology / Case number: #22212J
Ahmed Ghoniem / Sossina Haile / Mehdi Pishahang / Michael Bichnevicius / Asegun S Henry
Technology Areas: Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future
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Vibrating Ingestible BioElectronic Stimulator (VIBES)

Technology / Case number: #23759JQ
Robert Langer / Amro Alshareef / Shriya Sruthi Srinivasan / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Transforming Silicate Containing Materials into Reactive Materials for CO2 Capture and Other Applications

Technology / Case number: #24493J
Matthew Kanan / Joshua Rabinowitz / Yuxuan Chen / Benjamin Charnay / Rishi Agarwal / Wei Lun Toh / Yogesh Surendranath
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future
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Maximizing Carbon Efficiency in CO2 Electrolyzers: Complete Conversion of Bicarbonate to Formate

Technology / Case number: #24910
Ju Li / Zhichu Ren / Zhen Zhang
Technology Areas: Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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A Handheld Closed-Loop Automatic Insulin Delivery System

Technology / Case number: #22018J
Giovanni Traverso / Canchen Li / Erin Raftery / Sean You / Hen Wei Huang
Technology Areas: Biotechnology / Communication Systems / Drug Delivery
Impact Areas: Healthy Living
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Daniel Anderson / Idris Raji / Jacob Witten / Allen Jiang / Luke Rhym
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Daniel Anderson / Idris Raji / Akiva Gordon / Bowen Li
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Cellular Backpacks for Drug Delivery Across the Blood-Brain Barrier

Technology / Case number: #18547J
Robert Cohen / Natalya Klyachko / Yuling Zhao / Matthew Haney / Elena Batrakova / Roberta Polak / Michael F Rubner
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Electrochemical CO2 Conversion Architecture

Technology / Case number: #24598
Kripa K Varanasi / Simon Rufer
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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