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Reformer Enhanced Direct Injection Methanol Engines

Technology / Case number: #12864
Daniel Cohn / Leslie Bromberg
Technology Areas: Energy & Distribution
Impact Areas: Sustainable Future
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Method for Quantitative Monitoring of In Vivo Tumor Oxygenation

Technology / Case number: #19207JQ
Michael Cima / Ehud Schmidt / Robert Cormack / Larissa Lee / Gregory Ekchian
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Reprogram the Genome of M13 Phage for Vaccination and Immunotherapy Applications

Technology / Case number: #25169
Angela Belcher / Shengnan Huang
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Mechanical Underwater Soft Adhesion System for Kinetic Biosensing and Intelligent Targeted Drug Delivery

Technology / Case number: #26028J
Giovanni Traverso / Yubin Cai / Troy Ziliang Kang / Ming Zhao / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Expression Constructs for One-Step Construction of Allogeneic CAR-NK Cells

Technology, Tangible Property / Case number: #26118J
Jianzhu Chen / Fuguo Liu / Rizwan Romee
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Connected World
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Using a Genetically Modified Human IPS Line to Screen for Drugs that Prevent or Treat Alzheimer's Disease

Technology / Case number: #26292P
Li-Huei Tsai / Masayuki Nakano / Matheus Victor / Leyla Akay / TaeHyun Kim
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Microwave Sensing for Determination of Loading of Filters

Technology / Case number: #12205
Leslie Bromberg
Technology Areas: Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Sustainable Future, Connected World
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Amplitude Spectroscopy of a Solid-State Artificial Atom

Technology / Case number: #13407L
Karl Berggren / William Oliver
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Capillary-Film-Evaporative-Cooling Heat Exchanger and Its Associated Thermodynamic Processes

Technology / Case number: #25543
Gang Chen / Yaodong Tu
Technology Areas: Energy & Distribution
Impact Areas: Sustainable Future
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Synergisms between Small Molecule Boosters and LNP Formulations Uncovered using High Throughput Screening and Machine Learning

Technology / Case number: #26199J
Giovanni Traverso / Deepak Subramanian / Rajib Dey / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

LNP Automation Screening System

Technology / Case number: #26217
Robert Langer / Zhiling Zheng / Xin Yang / Linzixuan Rhoda Zhang / Ana Jaklenec
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Amorphous Solid Protein Microparticles via Solvent-Based Dehydration

Technology / Case number: #26228
Patrick Doyle / Talia Zheng
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Discovery and Engineering of Novel Integrases for High-Efficiency Gene Integration

Technology / Case number: #23554
Omar Abudayyeh / Justin Lim / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Lipid-Like Materials for Applications in siRNA Delivery

Technology / Case number: #15420
Robert Langer / Joseph Dorkin / Yunlong Zhang / Arturo Vegas / Kathryn Whitehead / Daniel Anderson
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

2-Aminoindole-Class Antimalarials

Technology / Case number: #14097BJ
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Programmable Insertion Approaches Via Reverse Transcriptase Recruitment

Technology / Case number: #23685
Omar Abudayyeh / Kaiyi Jiang / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Self-Correcting GKP Qubit in a Superconducting Circuit with an Oscillating Voltage Bias

Technology / Case number: #26191J
Max Geier / Frederik Nathan
Technology Areas: Energy & Distribution
Impact Areas: Connected World
License

1,3,5-triazinane-2,4,6-trione (TNT) Derivatives and Uses Thereof

Technology / Case number: #15446
Robert Langer / Hao Yin / Akinleye Alabi / Joseph Dorkin / Ahmed Eltoukhy / Yizhou Dong / Delai Chen / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Heterocycle-Modified Quinolines for Fluorescence-Based Protein Kinase Sensing

Technology / Case number: #13876
Barbara Imperiali
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
License

Compositions and Methods to Deliver RNA to Extracellular Matrix Producing Cells

Technology / Case number: #25390J
Daniel Anderson / Dennis Shi / Theresa Raimondo / Sho Toyonaga
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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