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Composition and Methods to Generate Assymetric Bispecific Antibodies from a Single Cell Line

Technology / Case number: #17698
Ram Sasisekharan / Andrew Hatas / Eduardo Fleischer / Vidya Subramanian / Kannan Tharakaraman
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Selective Metal-Mediated Arylation of Dichalcogenides in Biomolecules

Technology / Case number: #17814
Stephen Buchwald / Daniel Cohen / Chi Zhang / Bradley L. Pentelute
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Platform for High-Resolution Genome Mapping

Technology / Case number: #19244
Rajeev Ram / Huaiyu Meng
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Electronics & Photonics
Impact Areas: Healthy Living
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Measuring Single-Cell Biophysical Properties by Acoustical Scattering in Microchannels

Technology / Case number: #19506
Scott Manalis / Joon Ho Kang / Selim Olcum
Technology Areas: Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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An RNA Sequencing Method for Absolute Quantification of RNA Molecules

Technology / Case number: #20363
Peter C Dedon / Jennifer Hu / Bo Cao / Michael DeMott
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Functionalization of Protective Antigen by Chemical Conjugation

Technology / Case number: #20802
Bradley L. Pentelute / Zeyu Lu
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Micro Physiological Model for ALS

Technology / Case number: #20857
Roger Kamm / Tatsuya Osaki / Sebastien Uzel
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Microfluidic Device for the 3D and Compartmentalized Coculture of Neuronal and Muscle Cells, with Functional Force Readout

Technology / Case number: #18042
Roger Kamm / Sebastien Uzel
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Implantable Active Coil-based Transducers (ImpACTs) for Minimally-Invasive Biophysical Imaging

Technology / Case number: #20183
Alan Pradip Jasanoff / Aviad Hai / Virginia Spanoudaki
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Electronics & Photonics
Impact Areas: Healthy Living
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Integrated Mode-Locking Methods for On-Chip Mode-Locked Lasers

Technology / Case number: #18745
Erich P. Ippen / Patrick Callahan / Katia Shtyrkova / Michael Watts / Franz Kaertner
Technology Areas: Electronics & Photonics
Impact Areas: Connected World, Advanced Materials
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A LiDAR Device Based on Scanning Mirrors Array and Multi-Frequency Laser Modulation

Technology / Case number: #19166
Kamal Youcef-Toumi / Iman Bozchalooi
Technology Areas: Communication Systems / Electronics & Photonics / Sensing & Imaging
Impact Areas: Connected World
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Highly-Efficient Near-Field ThermoPhotoVoltaics Using Surface-Polariton Emitters and Thin-Film Photo Voltaic-Cell Absorbers

Technology / Case number: #18386
John D Joannopoulos / Aristeidis Karalis
Technology Areas: Electronics & Photonics / Energy & Distribution
Impact Areas: Sustainable Future
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A Platform for Continuous Directed Evolution in Human Cells

Technology / Case number: #19909
Matthew D. Shoulders / Samuel Hendel / Chet Berman / Christopher Moore / Louis Papa
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Concepts and Methods for Controlling Chemical Reaction Kinetics and Interaction Time in Large Systems

Technology / Case number: #18377
Kwanghun Chung / Jae Cho / Evan Murray
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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High-Throughput Native Context Mapping of the Regulatory Genome

Technology / Case number: #18012JQ
David K Gifford / Richard Sherwood / Nisha Rajagopal
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Continuous Freeze-Drying of Pharmaceuticals and Biopharmaceuticals in Unit Doses

Technology / Case number: #19494J
Bernhardt Trout / Capozzi Carlo / Roberto Pisano
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Method to Distinguish and Analyze White Blood Cells in the Presence of Red Blood Cells

Technology / Case number: #18889
Shivang Dave / Jason Tucker-Schwartz
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Electromechanical Lysis of Bacterial Pathogens using Ion Concentration Polarization

Technology / Case number: #19035
Jongyoon Han / Minseok Kim
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Atherofluidics-on-Chip

Technology / Case number: #18096
Joel Voldman / Sarvesh Varma
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Compositions and Methods for Treating and Preventing Obesity

Technology / Case number: #18085J
Manolis Kellis / Jan Korbel / Melina Claussnitzer
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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