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Injectable, Thermogelling, Prolonged-Release Hydrogel Formulations for CPG-ODNs

New
Technology / Case number: #26051J
Giovanni Traverso / Ameya Kirtane / Robert Langer / Avik Som / Jan-Georg Rosenboom / Eric Wehrenberg-Klee / Stephen Linderman
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Fluidic-Based Cell Capture and Adhesion Measurement Concept

New
Technology / Case number: #25888
Bert Joannes C Vandereydt / Sean Parks / Domitille Avalle / Kripa K Varanasi
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Spiral Integrated Optical Phased Arrays for Tunable Near-Field-Focusing Emission

New
Technology / Case number: #26247
Jelena Notaros
Technology Areas: Computer Science / Electronics & Photonics / Sensing & Imaging
Impact Areas: Connected World
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mRNA-based Myeloid Cell Stimulation Enhances Therapeutic Efficacy

New
Technology / Case number: #25731J
Ralph Weissleder / Akash Gupta / Kaelan Reed / Riddha Das / Christopher Garris / Daniel Anderson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Artificial Intelligence Training Core with Coincidence Counting Unit

New
Technology / Case number: #25350
Jeehwan Kim / Giho Lee
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Connected World
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Bridging Design Gaps: A Parametric Data Completion Approach With Graph-Guided Diffusion Models

New
Technology / Case number: #25903J
Nikos Arechiga / Faez Ahmed / Yanxia Zhang / Rui Zhou / Chenyang Yuan / Frank Permenter / Matt Klenk
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Connected World
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Self-Righting Systems, Methods, and Related Components

New
Technology / Case number: #20706JQ
Giovanni Traverso / Taylor Bensel / Alex Abramson / Minsoo Khang / Niclas Roxhed / Ester Caffarel Salvador / Robert Langer
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Methods And Design Of Optical Neural Network

Technology / Case number: #18794
Scott Skirlo / Dirk R Englund / Nicholas Harris / Yichen Shen / Mihika Prabhu / Jacques Johannes Carolan / Marin Soljacic
Technology Areas: Computer Science / Electronics & Photonics
Impact Areas: Uncharted Frontiers
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A Method for Hierarchical Time Series Reconciliation via Learning the Optimal Projection

Technology / Case number: #26179J
Georgia Perakis / Pin-Yu Chen / Yada Zhu / Asterios Tsiourvas / Wei Sun
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Sensing & Imaging
Impact Areas: Connected World
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Methods, Procedures, and Material Compositions to Formulate Thermally Stable Solid-State Lipid Nanoparticles via Drying at Ambient Conditions

Technology / Case number: #26177
Ana Jaklenec / Robert Langer / Mina Konakovic Lukovic / Jinbi Tian / Khanh Tran / Amy Lee
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Altered DNA Repair Pathway Engagement by Engineered CRISPR-Cas9 Nucleases

Technology / Case number: #23588
Vikash Pal Singh Chauhan / Robert Langer / Phillip Sharp
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Poly(-amino ester) Microparticles for Micronutrient Fortification

Technology / Case number: #22992
Ana Jaklenec / Robert Langer / Ruiqing Xiao / Linzixuan Rhoda Zhang
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
License

AO mRNA-LNP Stabilization

Technology / Case number: #26266
Ana Jaklenec / Robert Langer / Linzixuan Rhoda Zhang / Jooli Han / Tina Huang
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Systems, Devices, and Methods Utilizing Hybrid Photonic Crystal Cavities

Technology / Case number: #26325J
Dirk R Englund / Mark Dong / Andy Greenspon
Technology Areas: Computer Science / Electronics & Photonics / Energy & Distribution
Impact Areas: Connected World
License

Targeted Trans-splicing Using CRISPR-Cas Systems

Technology / Case number: #20505ER
Jacob Borrajo
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Plk1 inhibitor and Microtubule Poison Dual Payload Antibody Drug Conjugates for the Treatment of Cancer

Technology / Case number: #26136
Jesse C Patterson / Michael Yaffe
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Lipid-Polymer Microparticles (mLPM) For Thermostable, Pulsatile mRNA-LNP Vaccines

Technology / Case number: #26154
Ana Jaklenec / Robert Langer / Linzixuan Rhoda Zhang / Yuting Huang
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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System and Method for Enhancing Social Networks by Structural Modifications through Personalized Incentives

Technology / Case number: #15566TE
Yaniv Altshuler / Alex Paul Pentland
Technology Areas: Computer Science
Impact Areas: Connected World
License

Branched Poly(-amino esters) for the Delivery of Nucleic Acids

Technology / Case number: #20333JQ
Giovanni Traverso / Yunhua Shi / Ameya Kirtane / Grace Junyue Zhong / Daniel Reker / Robert Langer / Hyunjoon Kim / Netra Kamat / James Byrne / Gary Liu
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Composable Analytics

Technology / Case number: #16372L
Timothy Dasey / Micah Lee / Lars Fiedler / Ronald Locke / Kevin Nam / Rajendra Laad / Heather Griffin
Technology Areas: Computer Science
Impact Areas: Connected World
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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