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Nanosensors for Detecting and Imaging of Cancer Metastasis

Technology / Case number: #20490H
Sangeeta Bhatia / Liang Hao
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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A Multimodal Metric for Tracking Nociception Under Anesthesia

Technology / Case number: #20522J
Emery N Brown / Sandya Subramanian / Riccardo Barbieri
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Leveraging Device-arterial Coupling to Determine Cardiac and Vascular State

Technology / Case number: #20558J
Elazer R Edelman / Ahmad El Katerji / Quing Tan / Noam Josephy / Sonya Sanat Bhavsar / Steven Keller / Brian Chang
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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PROTAC Derivatives with Functional Handles for Chemical Conjugation/Modification

Technology / Case number: #20788J
Jeremiah A. Johnson / Aiden Wang / Michael Agius / Irene Ghobrial / Alexandre Detappe / Hung Nguyen / Yivan Jiang
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Immunostimulatory Nanoparticle Adjuvants

Non-Exclusively Licensed Technology / Case number: #20798HJ
Darrell J Irvine / Shane Crotty / Yu Kato / Murillo Silva
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Use of Choline Supplementation as Therapy for APOE4-Related Disorders

Technology / Case number: #20957WPJ
Li-Huei Tsai / Greg Sienski / Priyanka Narayan / Julia Bonner / Yuan-Ta Lin
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Structures with Complex Geometries and Controlled Porosity in Micrometer to Meter Dimensions Produced at Large Scale

Technology / Case number: #21002J
Yoel Fink / Ian Tafel / Dena Shahriari / Zi Jie Gabriel Loke / Polina Anikeeva
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Strong Adhesion of Wet Conducting Polymers on Diverse Substrates

Technology / Case number: #21093
Xuanhe Zhao / Akihisa Inoue / Hyunwoo Yuk
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Circular, Strained Zymogen

Technology / Case number: #21110J
Ronald T Raines / Ian Windsor
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Chimeric Antigen Receptor Signaling Domains Derived via Activity-based Directed Evolution

Technology / Case number: #21116
Michael Birnbaum / Taeyoon Kyung
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Rhinometric Sensing and Gas Detection

Technology / Case number: #21117
Ian Hunter / Nickolas Demas
Technology Areas: Sensing & Imaging
Impact Areas: Climate Stabilization
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Single-Dose Combination Immunotherapy Augments Responses to Checkpoint Blockades for the Treatment of Cancer

Technology / Case number: #21150H
Darrell J Irvine / Chensu Wang / Karl Dane Wittrup
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Arterial Wall Characterization in Optical Coherence Tomography Imaging

Technology / Case number: #21209
Elazer R Edelman / Lambros Anthanasiou / Max Olender
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Optimization of Circular Single Stranded DNA using M13 Phage

Technology / Case number: #21211
Angela Belcher / Tae-Gon Cha / Uyanga Tsedev / Christopher Voigt
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Ribonucleoprotein Approach to Boost the STING Signaling for Cancer Immunotherapy

Technology / Case number: #21216
Paula Hammond / Yanpu He / Jiahe Li
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Emboli Detection Methods to Identify Stroke Mechanism or Stroke Risk in Susceptible Adults and Children

Technology, Software / Case number: #21233J
Thomas Heldt / Barry Kussman / Kerri LaRovere / Syed Imaduddin
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Characterization and Utilization of a Subgenomic Promoter Mutant Library for Tuning Expression of Multiple Transgenes from Alphavirus Replicons

Technology / Case number: #21309
Ron Weiss / Jin Huh
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Design of an Externally Modulated Variable Excitation Raman Spectrometer

Technology / Case number: #21321
Ian Hunter / Michael Zervas
Technology Areas: Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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MicroRNA-based Logic Gates that Do Not Use Exogenous Proteins

Technology / Case number: #21334
Ron Weiss / Giulio Alighieri
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Fluid Assessment in Dialysis Patients by Point-of-Care Magnetic Relaxometry

Technology / Case number: #21339JQ
Michael Cima / Kristin Corapi / Herbert Lin / Christopher Frangieh / Ashvin Bashyam / Lina Colucci / Matthew Li
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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