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Invention Disclosure: Kinetic Sensing, Signal Generation, Feature Extraction, and Pattern Recognition for Control of Autonomous Wearable Leg Devices

Technology / Case number: #18945TE
Luke Mooney / Matthew Carney / Roman Stolyarov / Cameron Taylor / Hugh Herr
Technology Areas: Biotechnology / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Estimating Contractile Reserve using a Mechanical Circulatory Support Device

Technology / Case number: #25817J
Elazer Edelman / Steven Keller / Ahmad El Katerji / Jerald Curran
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Transdermal Optogenetic Peripheral Nerve Stimulation

Technology / Case number: #18928TE
Anthony Zorzos / Benjamin Maimon / Hugh Herr
Technology Areas: Biotechnology
Impact Areas: Healthy Living, Uncharted Frontiers
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A Stretchable, Wearable Ultrasound Transducer for Wide-Scale Breast Cancer Data Collection

Technology / Case number: #20934TE
Canan Dagdeviren / Lin Zhang
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Method for Zero Phase-Lag Real-Time Computation of Hilbert Transform and Analytic Signal

Technology / Case number: #18073TEJ
Edward Boyden / Nir Grossman / David Wang
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Neuromechanical Interventions for the Mitigation of Limb Pathology

Technology / Case number: #18430TE
Anthony Zorzos / Benjamin Maimon / Matthew Carty / Tyler Clites / Jean-Francois Duval / Shriya Srinivasan / Hugh Herr
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Methods and Apparatuses to Track Hand Configurations based on Ultrasound Signals

Technology / Case number: #25586
Xuanhe Zhao / Gengxi Lu
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living, Connected World
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Closed-Loop Noninvasive Brain Stimulation with Simultaneous Imaging to Control Cerebrospinal Fluid Flow in Humans

Technology / Case number: #25482
Laura Lewis / Joshua Levitt
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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Ingestible Electronics Integrated with Flexible Measurement Electrodes for Gastrointestinal Bioelectric Sensing

Technology / Case number: #23241
Carlo Giovanni Traverso / Robert Langer / Siheng You / So-Yoon Yang / Adam Gierlach / George Selsing
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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A Wavemeter-Enabled Swept Source Raman Spectroscopy System

Technology / Case number: #20066
Amir Atabaki / William Herrington / Rajeev Ram
Technology Areas: Biotechnology / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living, Connected World
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Software and Methods for Controlling Neural Responses in Deep Brain Regions

Technology / Case number: #20652M
James DiCarlo / Pouya Bashivan / Kohitij Kar
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living, Uncharted Frontiers
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A Handheld Closed-Loop Automatic Insulin Delivery System

Technology / Case number: #22018J
Carlo Giovanni Traverso / Hen Wei Huang / Siheng You / Erin Raftery / Canchen Li
Technology Areas: Biotechnology / Communication Systems / Drug Delivery
Impact Areas: Healthy Living
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Lipid Compositions for Delivery of Therapeutic Agents Comprising Cationic Lipids

Technology / Case number: #23842J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Compositions and Methods for Inhibiting Expression of the Signal Regulatory Protein Alpha Gene

Technology / Case number: #23695J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Luke Rhym / Allen Jiang / Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Closed-Loop Ingestible Robot for Radiation and Chemical Sensing

Technology / Case number: #22735
Carlo Giovanni Traverso / Hen Wei Huang / James Byrne
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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Electronic Sensing/Valve Application (Concept 3a Needle-less Drug Delivery)

Technology / Case number: #22659
Carlo Giovanni Traverso / Niclas Roxhed / Siheng You / Graham Arrick / Torben Sebastia Last
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Cellular Backpacks for Drug Delivery Across the Blood-Brain Barrier

Technology / Case number: #18547J
Roberta Polak / Elena Batrakova / Matthew Haney / Yuling Zhao / Natalya Klyachko / Michael Rubner / Robert Cohen
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Oleogel Drug Delivery Systems for Pediatric Applications

Technology / Case number: #22116J
Carlo Giovanni Traverso / Ameya Kirtane / Robert Langer / Aniket Wahane / Christina Karavasili
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Machine Learning for the Design of Cancer Vaccine Adjuvants

Technology / Case number: #21680J
Carlo Giovanni Traverso / Ameya Kirtane / Daniel Reker / Robert Langer / Lewis Scott Jones / Hyunjoon Kim / Netra Rajesh
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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