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A Mechanical Underwater Soft Adhesion System for Kinetic Biosensing and Intelligent Targeted Drug Delivery

Technology / Case number: #26028J
Giovanni Traverso / Yubin Cai / Troy Ziliang Kang / Ming Zhao / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Lithium-Ion Fiber Battery

Technology / Case number: #16676
Yoel Fink / Benjamin Grena
Technology Areas: Chemicals & Materials / Drug Delivery / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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Engineering Microbes and Metabolic Pathways for the Production of Ethylene Glycol from Xylose, Glucose, Carbohydrates and Renewable Resources

Technology / Case number: #15064
Gregory Stephanopoulos / Jose Avalos / Marjan De Mey / Brian Pereira / Deepak Dugar
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Zwitterionic Dopamine Sulfonate Coated Iron Oxide Nanoparticles

Technology / Case number: #15322
Moungi G Bawendi / He Wei / Hee-Sun Han / Numpon Insin
Technology Areas: Chemicals & Materials / Drug Delivery / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Injectable Hydrogel and Uses Thereof

Technology / Case number: #16662J
Robert Langer / Eric Appel / Weiheng Wang / Omid Veiseh / Matthew Webber / Kun Xue / Benjamin Tang / Yizhou Dong / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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The Design of DNA-scaffolded Subunit Vaccines for Enhanced Germinal Center Responses in HIV Vaccination

Technology / Case number: #25982H
Darrell J Irvine / Anna Romanov / Grant Knappe / Mark Bathe
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Advanced Materials
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Genomic Insertion of Large Cargo with Engineered Retro Elements

Technology / Case number: #23248
Omar Abudayyeh / Justin Lim / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Controlled Assembly of Lipid-Based Nanoparticles from Surfactant Micelles

Technology / Case number: #25418H
Darrell J Irvine / Ivan Pires / Paula Hammond
Technology Areas: Biotechnology / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Full-field Optical Coherence Microscopy System Using a Digital Focal Plane Array

Technology / Case number: #24144LJ
Guillermo Tearney / Michael Bradshaw / Osman Ahsen / Matthew Johnson / Joseph Gardecki
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Advanced Materials
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Scalable and High throughput Assembly of Layer-by-Layer Nanoparticles

Technology / Case number: #25554H
Darrell J Irvine / Ivan Pires / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Ionizable Lipid OF-02 and its Use in mRNA Delivery

Technology / Case number: #17733
Daniel Anderson / Rebecca McClellan / Kevin Kauffman / Owen Fenton / Joseph Dorkin
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Frameshift Suppressor tRNAs for Canonical Amino Acids

Technology / Case number: #21418TREJ
Kevin Esvelt / Ahmed Badran / Erika Alden DeBenedictis
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Advanced Materials
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Tunable Structure of Biodegradable Silk-Based Microcapsules for Soluble and Insoluble Payload Delivery

Technology / Case number: #23764J
Benedetto Marelli / Yagmur Yegin / Bernd Oschmann / Rupert Konradi / Ophelie Zeyons / Henning Urch / Pierre-Eric Millard / Muchun Liu
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Dissolvable Microcarriers for Adherent Cell Culture

Technology / Case number: #22052JDE
Krystyn Van Vliet / Ee Xien Ng
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Advanced Materials
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Daniel Anderson / Idris Raji / Jacob Witten / Allen Jiang / Luke Rhym
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Daniel Anderson / Idris Raji / Akiva Gordon / Bowen Li
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Ingestible Chemical Energy Harvesting System with Extended Lifetime

Technology / Case number: #23174
Giovanni Traverso / So-Yoon Yang / Jason Li
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Engineering a Swine Macro-Organ Colorectal Cancer Platform to Combat Transport-Induced Chemotherapy Resistance

Technology / Case number: #22864JQ
Robert Langer / Daniel Reker / Vance Soares / Yunhua Shi / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Oleogel Drug Delivery Systems for Pediatric Applications

Technology / Case number: #22116J
Robert Langer / Christina Karavasili / Aniket Wahane / Ameya Kirtane / Giovanni Traverso
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Crystalline and Amorphous Formulations Used to Deliver Anti-Fibrotic (and other) Compounds in Conjunction with Implanted Materials (Cells/Devices)

Technology / Case number: #18287J
Robert Langer / Shady Farah / Joshua Doloff / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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