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Circular, Strained Zymogen

Technology / Case number: #21110J
Ronald T Raines / Ian Windsor
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Single-Dose Combination Immunotherapy Augments Responses to Checkpoint Blockades for the Treatment of Cancer

Technology / Case number: #21150H
Darrell J Irvine / Chensu Wang / Karl Dane Wittrup
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Multi-Input miRNA Sensing with Constitutive ERNs to Regulate Multi-Output Gene Expression in Mammalian Cells

Exclusively Licensed Technology / Case number: #23123
Ron Weiss / Lei Wang / Wenlong Xu / Erez Pery / Deepak Mishra
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

3D Knit Spacesuit Sleeve with Multifunctional Fibers and Tunable Compression

Technology / Case number: #24607
Hugh M Herr / Christopher Shallal / Cody Paige / Rachel Bellisle / Jesus Guillermo Herrera Arcos / Ganit Goldstein / Atharva Sahasrabudhe / Volodymyr Korolovych / Lavender Tessmer / Svetlana V Boriskina / Skylar Tibbits / Dava Newman
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Uncharted Frontiers, Advanced Materials
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High Throughput Stochastic Bio-Molecular Sensor

Exclusively Licensed Technology / Case number: #24610
Ashwin Gopinath / Swathi Manda
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Diagnostics
Impact Areas: Healthy Living

Polystyrene Coated Magnetic Beads Serving as Raman Reporter for Simultaneous Target Binding and Identification

Technology, Tangible Property / Case number: #25081
Loza Tadesse / Nikiwe Mhlanga / Jongwan Lee / Marissa Morales
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Eye Drop Positioning Device with Haptic Feedback

Technology / Case number: #25116
Benjamin Lahner / Jesse George-Akpenyi / Carly Smith / Seung Hyeon Shim
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Mechanisms for Controlled Volume Injection into a Soft Media with Concurrent Pressure Measurement

Technology / Case number: #25109
Alexander Slocum / Sarah Sams / Andre Pincot / Joseph Morales / Emily Sologuren / Brendan Unikewicz / Tal Cohen / Nevan Hanumara
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Tuning Chloroplast Transgene Expression from Synthetic Operon

Technology / Case number: #25494
Christopher Voigt / Qiguo Yu
Technology Areas: Agriculture & Food / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Improved Treatment for Organ Regeneration and Blocking Scar Formation

Technology / Case number: #25302
Ioannis Yannas
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Molecular Time Capsules Enable Transcriptomic Recording in Living Cells

Technology / Case number: #25337
Gene-Wei Li / Dylan McCormick / Jack Rubien / Mirae Parker
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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An Efficient Bioconjugation Technology for Site-Selective Covalent Modification of Antibodies using an Engineered Affinity Peptide

Exclusively Licensed Technology / Case number: #25358
Bradley L. Pentelute / Katsushi Kitahara / Aurelie Rondon / Heemal Dhanjee / Jacob Rodriguez / Andrei Loas
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Programmable Lipid Nanoparticle Delivery via Corona Protein Engineering

Technology / Case number: #25165J
Omar Abudayyeh / Alisan Kayabolen / Cian Schmitt-Ulms / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Single Injection for mRNA

Exclusively Licensed Technology / Case number: #25224Q
Robert Langer / Jooli Han / Linzixuan Zhang / John Daristotle / Ana Jaklenec
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials

Multiplexed Expansion Revealing

Technology / Case number: #24562MH
Edward Stuart Boyden / Margaret Schroeder / Jinyoung Kang
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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A Machine Learning-guided Whole-Organ Optical Imaging Technique for Non-destructive Identification of Early Pre-Cancer Lesions and Harvesting of Viable Cells from the same for Organoid Culture

Technology / Case number: #25480
Angela Belcher / Vivek Rastogi / Neelkanth Manoj Bardhan
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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Hybrid Hydrogel to Support 3D Culture of Primary Human Cells

Technology / Case number: #25192
Linda Griffith / Samantha Holt
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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  • Women's Health
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Augmentation of T and B Cell Activation with a Novel Cysteine Protease Linker Sequence

Technology / Case number: #25338
Tyler Jacks / Sean-Luc Shanahan
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Methods for Machine-Learning Guided Protein Design

Technology / Case number: #25084
Omar Abudayyeh / Matteo Di Bernardo / Kaiyi Jiang / Jonathan S. Gootenberg
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Tool for Spatially Targeted Access and Placement of Hardware or Drugs in Deep or Consolidated Tissues

Technology / Case number: #25071
Robert Langer / Alexander Madinger / Shriya Sruthi Srinivasan
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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