Uses of Amphiphiles in Immune Cell Therapy and Compositions Therefore

Provided herein are methods for stimulating an immune response to a target cell population or a target tissue in a subject by administering to the subject a composition comprising an amphiphilic ligand conjugate. Such an amphiphilic ligand conjugate can comprise a lipid, one or more cargos (e.g., a CAR ligand, a chimeric cytokine receptor target, a chimeric co-stimulation receptor target, a synNotch receptor target), and optionally a linker.

Researchers

Peter DeMuth / Darrell J Irvine

Departments: David H Koch Institute for Integrative Cancer Res
Technology Areas: Chemicals & Materials: Polymers / Therapeutics: Proteins & Antibodies, Small Molecules
Impact Areas: Healthy Living

  • uses of amphiphiles in immune cell therapy and compositions therefor
    United States of America | Published application | 0
  • uses of amphiphiles in immune cell therapy and compositions therefor
    European Patent Convention | Published application
  • uses of amphiphiles in immune cell therapy and compositions therefor
    Japan | Published application
  • uses of amphiphiles in immune cell therapy and compositions therefor
    Hong Kong | Pending

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