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Modifications and Coatings to Improve Biocompatibility of Neurological Implants

Exclusively Licensed Technology / Case number: #19323J
Robert Langer / Robert Hevner / Samuel Browd / Brian Hanak / William Shain / Omid Veiseh / Daniel Anderson
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

Identifying Signaling Pathways from Phosphoproteomic and Transcriptional Data

Exclusively Licensed Technology / Case number: #13355WJ
David Karger / Shao-shan Huang / Laura Riva / Esti Yeger-Lotem / Ernest Fraenkel
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Peptide and Protein Modification to Afford Sox-Based Kinase Sensors

Exclusively Licensed Technology / Case number: #12133Q
Barbara Imperiali / Dora Carrico-Moniz / Elvedin Lukovic
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Molecular Determinants of Human Adaptation of H5N1 Influenza A Virus Hemagglutinin

Exclusively Licensed Technology / Case number: #14274
Rahul Raman / Kannan Tharakaraman / Karthik Viswanathan / Ram Sasisekharan
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Combination Therapies for Prostate and Breast Cancer with Abiraterone

Exclusively Licensed Technology / Case number: #16690Q
Michael Yaffe / Jesse C Patterson
Technology Areas: Therapeutics
Impact Areas: Healthy Living

Bortezomib Prodrugs

Exclusively Licensed Technology / Case number: #20771JQ
Jeremiah A. Johnson / Irene Ghobrial / Alexandre Detappe / Hung Nguyen / Yivan Jiang / Paiman Ghoroghchian
Technology Areas: Therapeutics
Impact Areas: Healthy Living

Molecular Design of Antibodies with Enhanced Stability

Non-Exclusively Licensed Technology / Case number: #13229J
Bernhardt Trout / Veysel Kayser / Vladimir Voynov / Bernhard Helk / Naresh Chennamsetty
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Single Injection Delivery Systems

Exclusively Licensed Technology / Case number: #16746JQ
Robert Langer / Kevin McHugh / James Norman / Stephany Tzeng / Thanh Nguyen / William Gates / Boris Nikolic / Phillip Eckhoff / Lowell Wood / Ana Jaklenec / No Inventor
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Intracellular Delivery to Red Blood Cells

Exclusively Licensed Technology / Case number: #17754
Klavs F. Jensen / James Abshire / Armon Sharei / Jacquin Niles
Technology Areas: Biotechnology
Impact Areas: Healthy Living

Synthetic Oncolytic LNP-Replicon RNA for Cancer Immunotherapy

Exclusively Licensed Technology / Case number: #21306HJQ
Darrell J Irvine / Noor Momin / Yingzhong Li / Yizhou Dong / Ron Weiss / Karl Dane Wittrup
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Light-gated Ion Channels with Fast Kinetics and High Sensitivity

Exclusively Licensed Technology / Case number: #16950TEJ
Gane Wong / Adam Cohen / Daniel Hochbaum / Yongku Cho / Nathan Klapoetke / Edward Stuart Boyden / Brian Chow
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living

Adhesive Microstructures with Thin Glue Coating

Exclusively Licensed Technology / Case number: #15983J
Robert Langer / Maria Jose Pereira / Woo-Kyung Cho / Jeffrey Michael Karp
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living, Advanced Materials

A Dual-Barreled Medical Injector

Exclusively Licensed Technology / Case number: #23529
Kripa K Varanasi / Vishnu Jayaprakash
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Self-lubricating Surfaces for Food Packaging and Food Processing Equipment

Technology / Case number: #15511
Kripa K Varanasi / Brian Solomon / Rajeev Dhiman / Jonathan Smith / Adam Paxson / Christopher Love
Technology Areas: Agriculture & Food / Chemicals & Materials
Impact Areas: Healthy Living, Sustainable Future
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Enhanced Polypeptide Synthesis by Inline Reagent Pretreatment

Exclusively Licensed Technology / Case number: #17541
Klavs F. Jensen / Alexander Mijalis / Dale Thomas / Mark Simon / Bradley L. Pentelute / Patrick Heider / Andrea Adamo
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

Directed Evolution of Synthetic Gene Cluster

Exclusively Licensed Technology / Case number: #15653
Christopher Voigt / Michael Smanski / Dehua Zhao
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Compositions and Methods for Promoting Hemostasis and other Physiological Activities.

Exclusively Licensed Technology / Case number: #12061J
Gerald Schneider / Yu Xiang Liang / David Tay / Kwok-Fai So / Rutledge Ellis-Behnke
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living

Single-Shot Full-Field Reflection Phase Microscopy

Non-Exclusively Licensed Technology / Case number: #14694J
Michael Feld / Toyohiko Yamauchi / Zahid Yaqoob / Wonshik Choi / Ramachandra Dasari
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
License

Spatial-Charge-Map (SCM): A High- Throughput Method for Antibody Screening Based on their Viscosity

Non-Exclusively Licensed Technology, Software / Case number: #15981J
Bernhardt Trout / Neeraj Agrawal / Bernhard Helk
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Rational Design of Affinity Improvement of Dengue 4e11 Antibody

Exclusively Licensed Technology / Case number: #15783
Ram Sasisekharan / Kannan Tharakaraman / Luke Robinson
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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