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Methods and Compositions of Matter for Activating Class I Histone Deacetylases (HDACs) for Treatment of Human Disease

Technology / Case number: #14951PJHQ
Li-Huei Tsai / Debasis Patnaik / Ling Pan / Stephen Haggarty
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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A Novel Method to Treat Myocardial Infarction and Other Tissue Damage Using Apolipoprotein D (apoD)

Technology / Case number: #15466
Monty Krieger / Kosuke Tsukamoto
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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Thiol-yne Mediated Synthesis of Multi-Tailed Lipids for siRNA Delivery

Technology / Case number: #15846
Robert Langer / Akinleye Alabi / Kevin Love / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Novel Method for the Detection of Anticoagulants in Plasma and Whole Blood

Technology / Case number: #19252J
James Fox / Charles Vanderburg / Pavan Bendapudi / Galit H. Frydman / Mehmet Toner / Ronald Tompkins
Technology Areas: Diagnostics
Impact Areas: Healthy Living
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Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids

Technology / Case number: #16016J
Mo Movassaghi / Karen Morrison / Paul Hergenrother / Justin Kim / Nicolas Boyer
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Injectable Hydrogel and Uses Thereof

Technology / Case number: #16662J
Robert Langer / Eric Appel / Weiheng Wang / Omid Veiseh / Matthew Webber / Kun Xue / Benjamin Tang / Yizhou Dong / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Inhalable Nanosensors with Volatile Reporters for Rapid Pathogen Identification in Respiratory Infections

Technology / Case number: #20307HL
Rod Kunz / Melodi Anahtar / Leslie Chan / Sangeeta Bhatia
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Reversible Covalent Modification for Improving Protein Delivery

Technology / Case number: #16581HQ
Darrell J Irvine / Li Tang
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Method for Predicting Patient Outcomes from a Quasi-Periodic Patient Signal

Technology / Case number: #16302
John Guttag / Yun Liu / Collin M Stultz
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Healthy Living
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Multilayer Porous Hydrogel for Robust Sensing of Macromolecules with Florescent Carbon Nanotube Sensors

Technology / Case number: #15892
Michael S. Strano / Nigel Reuel
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living
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DNA Instructional Model

Technology / Case number: #17291
J. Kim Vandiver / Kathleen Mead Vandiver / Bethany Lemanski
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Self-Assembled (Poly-(L-Glutamic Acid-PEG-Drug)-PLGA Micelles for Multistage Nanoparticle Delivery System

Technology / Case number: #14877J
Moungi G Bawendi / Dai Fukumura / Cliff Wong / Rakesh K. Jain
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Develop New Lethal Mutagens for Viral Diseases

Technology / Case number: #16089
John M Essigmann / Katherine Silvestre / Deyu Li
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Ironless Cyclotron

Technology / Case number: #16121
Leslie Bromberg / Peisi Le / Philip Michael / Timothy Antaya / Joseph V. Minervini / Alexey Radovinsky
Technology Areas: Electronics & Photonics / Energy & Distribution
Impact Areas: Healthy Living, Sustainable Future
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High Voltage Organic Semiconductor Based Thin Film Transistor

Technology / Case number: #15405
Akintunde Ibitayo Akinwande / Melissa Smith
Technology Areas: Electronics & Photonics / Industrial Engineering & Automation
Impact Areas: Healthy Living, Sustainable Future
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Genomic Insertion of Large Cargo with Engineered Retro Elements

Technology / Case number: #23248
Omar Abudayyeh / Justin Lim / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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3D Topological Nanofabrication in Hydrogel Scaffold

Technology / Case number: #25838HMJ
Peter So / Takahiro Nambara / Quansan Yang / Yuichiro Kunai / Edward Stuart Boyden
Technology Areas: Chemicals & Materials
Impact Areas: Healthy Living
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Ligand-Inducible Post-Transcriptional Gene Regulation Using Protein-Binding RNA Aptamers

Technology / Case number: #13998J
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Dendrimer and Peptide Based Excipients for the Attenuation of Protein Aggregation

Technology / Case number: #14184
Bernhardt Trout
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation / Therapeutics
Impact Areas: Healthy Living
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Tissue Specific Delivery of Interfering RNA

Technology / Case number: #13947H
Sangeeta Bhatia
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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