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Methods of Multiplexing CRISPR

Technology / Case number: #21646TE
Kevin Esvelt / Mariah Savoie (Avila) / Elizabeth Strait / Emma Chory
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Rapid Droplet-Based Systems for Antibody Drug Discovery

Technology / Case number: #23890J
Brandon DeKosky / Matias Gutierrez Gonzalez / Cheng-yu Chung / Ahmed Fahad / Nicoleen Boyle / Shuyan Jin
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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High-throughput Electroporation Device

Technology / Case number: #21871
Cullen Buie / Po-Hsun Huang / Sijie Chen
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Brain-Computer Interface for User's Visual Focus Detection

Technology / Case number: #20246
Alexandre Armengol Urpi / Sanjay Sarma
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology
Impact Areas: Healthy Living, Uncharted Frontiers, Connected World
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Purification of Substances Using CO2 Sub-and Super-Critical Fluid Chromatography

Technology / Case number: #19742
William Dalzell / John Moses / Veronica Wilson / Mariya Layurova / Tony Elian / Truong Cai / John MacKay / Clark Colton
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Sustainable Future
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Single Cell Super-Resolution Proteomics

Technology / Case number: #24088
Mark Harnett / Dimitra Vardalaki
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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Synthesis of Covalent Protein Dimers that can Inhibit MYC-Driven Transcription

Technology / Case number: #23305WJ
Bradley Pentelute / Isaac Klein / Carly Schissel / Sebastian Pomplun / Andrei Ioan Loas / Jacob Rodriguez / Muhammad Jbara / Ann Boija / Susana Hawken / Charles Li / Stephen Buchwald
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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RNA-Loaded Lipid Nanoparticle (LNP)

Technology, Tangible Property / Case number: #24973H
Byungji Kim / Darrell Irvine
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Target for Modulating Body Mass

Technology / Case number: #21326
Nikola Ivica / Yingzhong Li / Ting Dong / Jianzhu Chen
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Programmable RNA Writing with the Novel RNA-Guided RNA-Targeting CRISPR-Cas7-11 Enzyme

Technology / Case number: #24072
Omar Abudayyeh / Jonathan Gootenberg / Wenyuan Zhou / Cian Schmitt-Ulms / Alisan Kayabolen
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Structure and Engineering of the Type III-E CRISPR-Cas7-11 Effector Complex

Technology / Case number: #23945J
Omar Abudayyeh / Jonathan Gootenberg / Wenyuan Zhou / Hiroshi Nishimasu / Kazuki Kato / Cian Schmitt-Ulms
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Nanoparticle Conjugates of Highly Potent Toxins

Technology / Case number: #19222
Paiman Ghoroghchian / Ruogu Qi
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Microfluidic Device for the 3D and Compartmentalized Coculture of Neuronal and Muscle Cells, with Functional Force Readout

Technology / Case number: #18042
Roger Kamm / Sebastien Uzel
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Extensible Recombinase Cascades

Technology / Case number: #18532
Timothy Lu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Synthetic Cell/Condition-Specific Promoters and Enhancers

Technology / Case number: #18570
Timothy Lu / Lior Nissim / Ming Ru Wu
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Transcriptional Sensor for Bile Acids in Bacteroides Thetaiotaomicron

Technology / Case number: #18573
Christopher Voigt / Mao Taketani
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Particle Isolation/Enrichment Using Continuous Closed-Loop Spiral Microfluidics

Technology / Case number: #18940
Kyungyong Choi / Hyunryul Ryu / Jongyoon Han
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Implantable Active Coil-based Transducers (ImpACTs) for Minimally-Invasive Biophysical Imaging

Technology / Case number: #20183
Virginia Spanoudaki / Aviad Hai / Alan Jasanoff
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Electronics & Photonics
Impact Areas: Healthy Living
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Miniaturization of External Mechanical Vibration for Ultrasound Shear Wave Elastography Imaging

Technology / Case number: #20289
Brian Anthony / Heng Yang / Felix Van De Donk
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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A Nanoscale Interface for Cross-modal Medical Imaging

Technology / Case number: #20367
Virginia Spanoudaki / Aviad Hai / Robert Langer / Daniel Anderson / Alan Jasanoff
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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