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Fluidic-Based Cell Capture and Adhesion Measurement Concept

Technology / Case number: #25888
Kripa K Varanasi / Domitille Avalle / Sean Parks / Bert Joannes C Vandereydt
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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mRNA-based Myeloid Cell Stimulation Enhances Therapeutic Efficacy

Technology / Case number: #25731J
Daniel Anderson / Christopher Garris / Riddha Das / Kaelan Reed / Akash Gupta / Ralph Weissleder
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Hardware Models of Biochemical Reaction Networks

Technology / Case number: #13076
Rahul Sarpeshkar
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Non-Invasive Sensory Stimulation Modifies the Microbiome-Gut-Brain Axis and Engages Insular-Vagal Circuitry

Technology / Case number: #25760P
Li-Huei Tsai / Jung Park / Ravikiran Raju / Cheng-Yi Yang / Lorenzo Bozzelli / Daniela Rodrigues Amorim
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Platform for Label-Free Recording/Imaging Metabolic Activity and Status in Cells

Technology / Case number: #25931P
W. David Lee / Rebecca Zubajlo / Tatsuya Osaki / Xiang (Shawn) Zhang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Machine Learned Chemical Intuition for the AI Generation of Molecules within Specific Chemical Spaces

Technology / Case number: #26403
Brett McGuire / Zachary Fried
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Seqwell Ancillary Tools and Assays Including StimSeq and Spatial Barcoding

Technology / Case number: #19508
J. Christopher Love / Marc Wadsworth / Travis Hughes / Alex Shalek / Todd Gierahn
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Colloidal Hydrogel Particles with tunable Chemistry, Geometry, and Flexibility

Technology / Case number: #13461J
Mehmet Toner / Patrick Doyle
Technology Areas: Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Methods for Improving Statistical Power in Genetic Discovery by Incorporating Quality Control Flags

Technology / Case number: #25839P
Manolis Kellis / Yosuke Tanigawa
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Hand Exoskeleton System for Data Collection

Technology / Case number: #26180
Edward Adelson / Arthur Hu / Haoshu Fang / Pulkit Agrawal / Branden Romero
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Weight Sensing

Technology / Case number: #26101
Alexander Slocum / Lorenzo Stratta / Rohan Kadambi / Steven Burcat / Roberto Pisano / Richard D Braatz / Bernhardt Trout
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Synergisms between Small Molecule Boosters and LNP Formulations Uncovered using High Throughput Screening and Machine Learning

Technology / Case number: #26199J
Giovanni Traverso / Deepak Subramanian / Rajib Dey / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Programmable Addition Via Site-Specific Targeting Elements (PASTE)

Technology / Case number: #22225
Omar Abudayyeh / Jonathan S. Gootenberg
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Multimodal and Network Phenotyping based on Single-Organelle In Situ Multiplexed Imaging

Technology / Case number: #25842
Mark Bathe / Reuven Falkovich
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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An Information-Theoretic Approach for Analyzing Chromatin State Models

Technology / Case number: #17666
Manolis Kellis / Wouter Meuleman
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Translocation of Non-Natural Chemical Entities Through Anthrax Protective Antigen Pore

Technology / Case number: #15639J
Bradley L. Pentelute / R. Collier / Gizem Akcay / Jingjing Ling / Amy Rabideau / Xiaoli Liao
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Glucose-Responsive Insulin Formulations Using Chemically Modified Insulin Derivatives and Non-Covalent Insulin-Binding Molecules

Technology / Case number: #15976J
Robert Langer / Rosemary Kanasty / Matthew Webber / Kun Xue / Hung-Chieh (Danny) Chou / Benjamin Tang / Yunlong Zhang / Yair Levi / Arturo Vegas / Daniel Anderson
Technology Areas: Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living
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Distinct Gene Systems Mediating Activity-Dependent Plasticity in Visual Cortex

Technology / Case number: #11841P
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Glucose Valve and Other Metabolite Valves

Technology / Case number: #12369
Kristala L Jones Prather
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Reverse Micelle Nanoprecipitation: A Method for Encapsulating Nucleic Acids in Biodegradable Polymers

Technology / Case number: #12561J
Robert Langer / Liangfang Zhang / Aleksandar Radovic-Moreno / Omid Farokhzad
Technology Areas: Chemicals & Materials / Computer Science / Electronics & Photonics
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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