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Fluidic-Based Cell Capture and Adhesion Measurement Concept

New
Technology / Case number: #25888
Bert Joannes C Vandereydt / Sean Parks / Domitille Avalle / Kripa K Varanasi
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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mRNA-based Myeloid Cell Stimulation Enhances Therapeutic Efficacy

New
Technology / Case number: #25731J
Ralph Weissleder / Akash Gupta / Kaelan Reed / Riddha Das / Christopher Garris / Daniel Anderson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Altered DNA Repair Pathway Engagement by Engineered CRISPR-Cas9 Nucleases

Technology / Case number: #23588
Vikash Pal Singh Chauhan / Robert Langer / Phillip Sharp
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Targeted Trans-splicing Using CRISPR-Cas Systems

Technology / Case number: #20505ER
Jacob Borrajo
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Plk1 inhibitor and Microtubule Poison Dual Payload Antibody Drug Conjugates for the Treatment of Cancer

Technology / Case number: #26136
Jesse C Patterson / Michael Yaffe
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Colloidal Hydrogel Particles with tunable Chemistry, Geometry, and Flexibility

Technology / Case number: #13461J
Patrick Doyle / Daniel Pregibon / Ramin Haghgooie / Mehmet Toner
Technology Areas: Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Methods for Microbial Oil Overproduction from Cellulosic Materials

Technology / Case number: #15695
Mitchell Tai / Gregory Stephanopoulos
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Healthy Living, Sustainable Future
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Hand Exoskeleton System for Data Collection

Technology / Case number: #26180
Branden Romero / Pulkit Agrawal / Edward Adelson / Haoshu Fang / Arthur Hu
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Expression Constructs for One-Step Construction of Allogeneic CAR-NK Cells

Technology, Tangible Property / Case number: #26118J
Rizwan Romee / Fuguo Liu / Jianzhu Chen
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Connected World
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Methods for Improving Statistical Power in Genetic Discovery by Incorporating Quality Control Flags

Technology / Case number: #25839P
Manolis Kellis / Yosuke Tanigawa
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Reprogram the Genome of M13 Phage for Vaccination and Immunotherapy Applications

Technology / Case number: #25169
Shengnan Huang / Angela Belcher
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Using a Genetically Modified Human IPS Line to Screen for Drugs that Prevent or Treat Alzheimer's Disease

Technology / Case number: #26292P
Li-Huei Tsai / TaeHyun Kim / Leyla Akay / Matheus Victor / Masayuki Nakano
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Weight Sensing

Technology / Case number: #26101
Richard D Braatz / Roberto Pisano / Steven Burcat / Alexander Slocum / Rohan Kadambi / Lorenzo Stratta / Bernhardt Trout
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Synergisms between Small Molecule Boosters and LNP Formulations Uncovered using High Throughput Screening and Machine Learning

Technology / Case number: #26199J
Giovanni Traverso / Ameya Kirtane / Rajib Dey / Deepak Subramanian
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Oxygenating Reservoir for Culture Media in Microphysiological Systems

Technology / Case number: #25858
Linda Griffith / Priyatanu Roy / Sydney Kim / Matthew Johnson / David L Trumper
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Discovery and Engineering of Novel Integrases for High-Efficiency Gene Integration

Technology / Case number: #23554
Omar Abudayyeh / Jonathan S. Gootenberg / Lukas Villiger / Justin Lim
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Programmable Addition Via Site-Specific Targeting Elements (PASTE)

Technology / Case number: #22225
Omar Abudayyeh / Jonathan S. Gootenberg
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Multimodal and Network Phenotyping based on Single-Organelle In Situ Multiplexed Imaging

Technology / Case number: #25842
Mark Bathe / Reuven Falkovich
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Olfactory Receptor-Based Devices

Technology / Case number: #12776TE
Manu Prakash / Andreas Mershin / Brian Cook / Joanke (Johanna) Bikker Graveland / Liselotte Kaiser / Shuguang Zhang / Yael Maguire / David Kong
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Transcriptional Engineering of Lactobacillus for Improved Lactic Acid Tolerance and Productivity at Low pH

Technology / Case number: #12783
Daniel Klein-Marcuschamer / Gregory Stephanopoulos
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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