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Compositions and Methods for Treating and Preventing Obesity

Technology / Case number: #18085J
Manolis Kellis / Jan Korbel / Melina Claussnitzer
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Multiplexed Specific Metalloprotease Activity Measurements

Technology / Case number: #19425DE
Steven Robert Tannenbaum / Evan Chiswick / Ravindra Kodihalli / Christi Cook / Caroline Chopko Ahrens / Miles Miller / Douglas Lauffenburger / Linda Griffith
Technology Areas: Biomaterials & Bioelectronics / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Open-Ended, Dicer-Cleavable Concatemeric siRNA Generated by Rolling Circle Transcription

Technology / Case number: #18076
Paula Hammond / Kevin Shopsowitz / Connie Wu
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Development of Multi-Specific Antibody-Serum Albumin Fusion Proteins Targeting Multiple Human and Murine CXC (ELR+) Chemokines

Technology / Case number: #19355JQ
Karl Dane Wittrup / Andrew Luster / Alessandro Angelini
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Biomedical Imaging and Optical Stimulation Device

Technology / Case number: #18022
Juejun Hu / Qi Qin / Tian Gu
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Diazene Directed Modular Synthesis of Oligocyclotryptamines

Technology / Case number: #18747
Mo Movassaghi / Petra Lindovska
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Sound Pressure Level Sensitive Passive Hearing Protector by Acoustic Metamaterials

Technology / Case number: #18005
Xuanlai Fang / Jun Xu
Technology Areas: Industrial Engineering & Automation
Impact Areas: Healthy Living
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Manufacture of Thermo-Responsive Hydrogel Composing of Drug-Nanocapsule for Sustainable Release of Ibuprofen, Ofloxacin and Dexamethasone

Technology / Case number: #18561
Jeremiah A. Johnson / Farrukh Vohidov / Qixian Chen
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Structured DNA Conjugates

Technology / Case number: #18588
Mark Bathe / Hyungmin Jun / Tyson Shepherd / Remi Veneziano / Sakul Ratanalert
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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High Molecular Weight, Post-Translationally Modified Proteins Brushes Through Tyrosine Modification Chemistry

Technology / Case number: #17927
Bradley D. Olsen / Brian Seifried
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Design of Mechanism for a Low-Cost, Completely Passive Prosthetic Knee for Users with Above-Knee Amputation

Technology / Case number: #17907
Amos Winter / Venkata Narayana Murthy Arelekatti / Daniel Dorsch
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Ultrasound-Based Absolute Scatterer Concentration Measurement Technique: Image Volume Estimation from Scatter Spread Function Extracted From the Image

Technology / Case number: #17865
Duane S Boning / John Lee / Brian Anthony
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Potentially Low-Cost and Transparent Sensor Array Systems for Cellular Monitoring and Smart Skin Applications

Technology / Case number: #17850
Tomas Palacios / Charles Mackin
Technology Areas: Biotechnology / Electronics & Photonics
Impact Areas: Healthy Living
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Digital Imaging Based Spectrometry for Analysis of Emulsions

Technology / Case number: #17835
Sanjay Emani Sarma / Pranay Jain
Technology Areas: Agriculture & Food / Biomaterials & Bioelectronics / Biotechnology / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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Synthetic Hybrid Receptor and Genetic Circuit in Probiotic Bacteria to Detect Enteric Pathogenic Microorganisms

Technology / Case number: #17801HJ
James Collins / Douglas Cameron / Ning Mao
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Nano-Fibular Nanoparticle Polymer-Drug Conjugate for Sustained Dermal Delivery of Retinoids

Technology / Case number: #17491
Paula Hammond / Mohiuddin Quadir / Steven Castleberry
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Healthy Living
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Layer-by-Layer Nanoparticles for Cytokine Therapy in Cancer Treatment

Technology / Case number: #20027H
Darrell J Irvine / Talar Tokatlian / Santiago Correa Echavarria / Antonio Barberio / Mariane Melo / Erik Dreaden / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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New Methods to Assess Fluid Distribution in Muscle Tissue via Single Sided Magnetic Resonance Sensors

Technology / Case number: #21335
Michael Cima / Christopher Frangieh / Ashvin Bashyam
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Methods and Compositions for Increasing Sensitivity of Cancer Cells to Glutaminase Inhibitors and Applications to Cancer Therapy

Technology / Case number: #19305
Matthew Vander Heiden / Laura Danai / Alexander Muir / Dan Gui
Technology Areas: Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Intracellular Calcium Sensors for MRI

Technology / Case number: #20143
Alan Pradip Jasanoff / Benjamin Bartelle / Ali Barandov
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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