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Fluidic-Based Cell Capture and Adhesion Measurement Concept

Technology / Case number: #25888
Kripa K Varanasi / Domitille Avalle / Sean Parks / Bert Joannes C Vandereydt
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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mRNA-based Myeloid Cell Stimulation Enhances Therapeutic Efficacy

Technology / Case number: #25731J
Daniel Anderson / Christopher Garris / Riddha Das / Kaelan Reed / Akash Gupta / Ralph Weissleder
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Non-Invasive Sensory Stimulation Modifies the Microbiome-Gut-Brain Axis and Engages Insular-Vagal Circuitry

Technology / Case number: #25760P
Li-Huei Tsai / Jung Park / Ravikiran Raju / Cheng-Yi Yang / Lorenzo Bozzelli / Daniela Rodrigues Amorim
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Platform for Label-Free Recording/Imaging Metabolic Activity and Status in Cells

Technology / Case number: #25931P
W. David Lee / Rebecca Zubajlo / Tatsuya Osaki / Xiang (Shawn) Zhang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Multimodal and Network Phenotyping based on Single-Organelle In Situ Multiplexed Imaging

Technology / Case number: #25842
Mark Bathe / Reuven Falkovich
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods for Increasing Safety of Embryonic Stem Cells

Technology / Case number: #13769
Clark Colton / Jeffrey Millman
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Extended Transient Transfection by Repeated Delivery of RNA

Technology / Case number: #13415
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Engineering Microbes and Metabolic Pathways for the Production of Ethylene Glycol from Xylose, Glucose, Carbohydrates and Renewable Resources

Technology / Case number: #15064
Gregory Stephanopoulos / Jose Avalos / Marjan De Mey / Brian Pereira / Deepak Dugar
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Method for the Characterization and Differentiation of Material Surfaces Using Compound Responses of Mechanically Driven Cells

Technology / Case number: #17585J
Dick Yue / Xiaoying Zhu / Roland Bouffanais
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Cellular Surface Engineering via Multilayered Polymer Nanostructures

Technology / Case number: #12846
Robert Cohen / Albert Swiston / Darrell J Irvine / Michael F Rubner
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Ultrasonic Method for Measuring Concentrations of Particles, Cells and Islets in Suspension

Technology / Case number: #11886J
Clark Colton
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids

Technology / Case number: #16016J
Mo Movassaghi / Karen Morrison / Paul Hergenrother / Justin Kim / Nicolas Boyer
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Full-field Optical Coherence Microscopy System Using a Digital Focal Plane Array

Technology / Case number: #24144LJ
Guillermo Tearney / Michael Bradshaw / Osman Ahsen / Matthew Johnson / Joseph Gardecki
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Advanced Materials
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A Dynamic Single-Cell Fragility Test that Assesses Red Blood Cell Membrane Integrity with Applications to Stored Blood

Technology / Case number: #25732J
Subra Suresh / Fang Kong / Ming Dao
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Method to Pattern Cells (Crude Blood) on a (Planar) Surface

Technology / Case number: #15262
Shivang Dave / German Serrano
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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In Vitro Human Blood Brain Barrier

Technology / Case number: #19918P
Li-Huei Tsai / Joel Blanchard
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Single-Cell RNA Sequencing Using Click-Chemistry

Technology / Case number: #20396
Phillip Sharp / D.B.Jay Mahat
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Bioinspired Design of Self-Adjuvanted C3d-Fusion SARS-CoV-2 mRNA Vaccines

Technology / Case number: #23326
Robert Langer / Allen Jiang / Bowen Li / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Nucleotide Depletion as Differentiation Therapy in the Treatment of Cancer

Technology / Case number: #21131J
Matthew Vander Heiden / Frances Diehl / David Sykes / Peggy Hsu
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Tissue Platform and Machine Learning Algorithm for Drug-Drug Transporter Interaction Discovery

Technology / Case number: #21883J
Robert Langer / Daniel Reker / Vance Soares / Yunhua Shi / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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