Structure and Engineering of the Type III-E CRISPR-Cas7-11 Effector Complex

Technology / Case number: #23945J
Omar Abudayyeh / Cian Schmitt-Ulms / Kazuki Kato / Hiroshi Nishimasu / Wenyuan Zhou / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Nucleic Acid-Conjugated Polymeric Nanoparticles for Gene Therapy

Technology / Case number: #23628JQ
Natalie Artzi / Alexander M Cryer / Pere Dosta Pons
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Daniel Anderson / Idris Raji / Akiva Gordon / Bowen Li
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Synthesis of Ester, Carbonate, and Carbamate-derived Novel Biodegradable Ionizable Lipids from Methyl Ricinoleate or Methyl 12-Hydroxystearate and its Applications

Technology / Case number: #23381Q
Daniel Anderson / Jacob Witten / rajith manan / Akiva Gordon / Bowen Li / Luke Rhym
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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M13 Phage based Gene Therapy Platform (Chapter 4 of Thesis Work)

Technology / Case number: #23296
Angela Belcher / Uyanga Tsedev
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Systems, Methods, And Compositions For RNA-Guided RNA-Targeting CRISPR Effectors from Type III Systems

Technology / Case number: #23239
Omar Abudayyeh / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Lipid Nanoparticles for Drug Delivery to Microglia in the Brain

Technology / Case number: #23156P
Robert Langer / William Ralvenius / Julia Bonner / Jason Andresen / Joel Blanchard / Owen Fenton / Li-Huei Tsai
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Novel Peptides to Inhibit Ena/VASP Proteins

Technology / Case number: #22897J
Amy Keating / Samantha Hill / Ghassan Mouneimne / Sara Parker / Meucci IIunga / Theresa Hwang
Technology Areas: Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Fusion Capsid Therapy for COVID-19 and Applies to Other Viruses: Universal "Dominant" Antiviral to Prevent Virus Evolution and Future Pandemics (DNA/RNA/Protein)

Technology, Tangible Property / Case number: #22801MH
Robert Langer / Bowen Li / Yong Qian / Alexi Choueiri / Edward Stuart Boyden / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Control Replication and Transcription of Self-Replicating RNA in Responses to Small Molecule TMP

Technology / Case number: #22331H
Darrell J Irvine / Parisa Yousefpour / Jan Lonzaric / Yingzhong Li / Ron Weiss
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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