Developing techniques and instrumentation for single cell analysis and cancer research
Background and Experience
Scott Manalis is the David H. Koch (1962) Professor of Engineering and faculty member in the departments of biological and mechanical engineering at MIT. He currently serves as Associate Department Head in the Department of Biological Engineering.
Dr. Manalis' laboratory develops quantitative and real-time techniques for single cell analysis, using conventional approaches to fabricate novel fluidic devices, and exploit the unique physical properties associated with micro- and nanoscale dimensions for developing precision measurement methods.
In cancer, the lab is interested in creating functional assays for precision medicine. They are developing new technology platforms for predicting therapeutic response in which biophysical properties of individual tumor cells are measured in response to ex vivo treatment in a broad range of tumor types, including leukemias, glioblastoma, colon and pancreatic cancers.
Professor Manalis received a BS in physics from the University of California, Santa Barbara, and a PhD in applied physics from Stanford University. Dr. Manalis is a founder of two companies (Travera and Affinity Biosensors) that utilize the suspended microchannel resonator for weighing single cells.
Technologies
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