Phillip Sharp

Background and Experience

Phillip A. Sharp, an Institute Professor emeritus at MIT, is a member of the Department of Biology and the Koch Institute for Integrative Cancer Research. He joined the Center for Cancer Research in 1974, serving as director from 1985 to 1991 before becoming head of the Department of Biology for eight years.

He was founding director of the McGovern Institute from 2000 to 2004. Sharp has authored over 500 papers. He is an elected member of the National Academy of Sciences, the National Academy of Medicine, the American Academy of Arts and Sciences, the American Philosophical Society, and the Royal Society, UK. Among his many awards are the Gairdner Foundation International Award, the Lasker Basic Medical Research Award, and the National Medal of Science. His long list of service includes the presidency of the AAAS and Chair of the Scientific Advisory Committee, SU2C Project, AACR. A native of Kentucky, Sharp earned a BA from Union College, Barbourville, KY, and a PhD in chemistry from the University of Illinois, Urbana-Champaign in 1969. His work studying the molecular biology of gene expression relevant to cancer and the mechanisms of RNA splicing earned Sharp the 1993 Nobel Prize in Physiology or Medicine.

Sharp is a member of the board of directors of the Whitehead and Broad Institutes, the Gairdner Foundation (Canada), and chairs the advisory boards of Fidelity Biosciences Group, SU2C/AACR Scientific Review Committee, ReMedy/IMol Institute (Poland), the MIT Museum, and the Jameel Clinic at MIT. Sharp is a co-founder of Biogen and of Alnylam Pharmaceuticals Inc. He is chairman of the scientific advisory board and member of the board of directors, Alnylam Pharmaceuticals; advisor and investor, Longwood and Polaris Venture Funds; member of the board of directors, Vir Biotechnology; and member of the scientific advisory board, Danahers, Dewpoint Therapeutics and Skyhawk Therapeutics.

Awards and Honors

In addition to the 1993 Nobel Prize in Physiology or Medicine, Dr. Sharp has won many notable awards including:

• Double Helix Medal | 2006
• National Medal of Science | 2004
• Benjamin Franklin Medal for Distinguished Achievement in the Sciences | 1999
• Louisa Gross Horwitz Prize | 1988
• Albert Lasker Basic Medical Research Award | 1988
• Gairdner Foundation International Award | 1986
• Alfred P. Sloan Jr. Prize | 1986
• Golden Plate Award | 1981

The genome is not the end of biology. The genome is actually just the beginning of biology. It is going to set us on a whole new plane or rate of discovery that will make it fascinating for decades to come. ”