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TOX Inhibitor and Molecular Glue

Technology / Case number: #25241
Angela Koehler / Bocheng Wu
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Oral Pill Water-Tight Payload Chamber Design with Triggerable Release

Technology / Case number: #25209J
Carlo Giovanni Traverso / Miguel Jimenez / James McRae / Emily Kolaya
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Methods and Apparatuses to Track Hand Configurations based on Ultrasound Signals

Technology / Case number: #25586
Xuanhe Zhao / Gengxi Lu
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living, Connected World
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Closed-Loop Noninvasive Brain Stimulation with Simultaneous Imaging to Control Cerebrospinal Fluid Flow in Humans

Technology / Case number: #25482
Laura Lewis / Joshua Levitt
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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A Microphysiological Model of the Brain Including Blood-brain Barrier, Neural Tissue and Meningeal Lymphatics

Technology / Case number: #24291
Roger Kamm
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Methods for Improving Cross-Ancestry Transferability in Predicting Polygenic Phenotypes from Genetic Variation

Technology / Case number: #24858
Manolis Kellis / Yosuke Tanigawa
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Ingestible Electronics Integrated with Flexible Measurement Electrodes for Gastrointestinal Bioelectric Sensing

Technology / Case number: #23241
Carlo Giovanni Traverso / Robert Langer / Siheng You / So-Yoon Yang / Adam Gierlach / George Selsing
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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Learning-Guided Electron Microscopy

Technology / Case number: #21380J
Yaron Meirovitch / Aravinathan Samuel / Lu Mi / Jeff Lichtman / Nir Shavit
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Healthy Living, Uncharted Frontiers
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matthew Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
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Multisensory Gamma Stimulation Promotes Glymphatic Clearance of Amyloid

Technology / Case number: #25696PH
Li-Huei Tsai / Edward Boyden / Ping-Chieh Pao / Cheng-Yi Yang / Mitchell Murdock
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Software and Methods for Controlling Neural Responses in Deep Brain Regions

Technology / Case number: #20652M
James DiCarlo / Pouya Bashivan / Kohitij Kar
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living, Uncharted Frontiers
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Visual Stimulus Generator Code for Controlling Neural Responses in Deep Brain Regions

Software / Case number: #21453M
James DiCarlo / Pouya Bashivan / Kohitij Kar
Technology Areas: Computer Science / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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NetCast: Low-Power Edge Computing with Optical Neural Networks via WDM Weight Broadcasting

Technology / Case number: #22737J
Dirk Englund / Ryan Hamerly
Technology Areas: Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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Unified Documentation and Information Retrieval for Electronic Health Records

Technology / Case number: #23636JQ
David Sontag / Luke Murray / Monica Agrawal / Steven Horng / Divya Gopinath / David Karger
Technology Areas: Computer Science
Impact Areas: Healthy Living, Connected World
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A Fully Differential Piezoelectric Microphone and Amplifier System for Cochlear Implants and Other Hearing Devices

Technology / Case number: #23776JQ
Hideko Nakajima / Aaron Yeiser / Elizabeth Olson / Lukas Graf / Christopher McHugh / Ioannis Kymissis / Jeffrey Lang
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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A Natural Language Diet Tracking Smartphone Application

Software / Case number: #19264
Mandy Korpusik / James Glass
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Communication Systems
Impact Areas: Healthy Living, Connected World
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Software to Extract Acoustic Features from Audio and Model Health Outcomes

Software / Case number: #20034
Tuka Al Hanai
Technology Areas: Computer Science / Sensing & Imaging
Impact Areas: Healthy Living, Connected World
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Software to Compute the Elastic Response of Thin Plates and Shells (Monolayers and Bilayers) to Growth

Software / Case number: #20823
Willem van Rees
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Sustainable Future
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Predictor of Deletions after Targeted Chromosome Cleavage

Technology / Case number: #21045
Max Shen / Jonathan Hsu / David Gifford
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living, Connected World
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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