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Protein Retrosplicing Enabled by a Double Ligation Reaction

Technology / Case number: #15368
Bradley L. Pentelute / Xiaoli Liao / Amy Rabideau / Jingjing Ling / Rocco Policarpo
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Articles and Methods for Modifying Condensation on Surfaces

Technology / Case number: #15462Q
Adam Paxson / Jonathan Smith / Sushant Anand / Kripa K Varanasi
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Connected World
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Engineered Probiotics for Urinary Cancer Diagnosis

Technology / Case number: #15881HJ
Tal Danino / Arthur Prindle / Jeff Hasty / Sangeeta Bhatia
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Methods for Treating Polycystic Kidney Disease

Technology / Case number: #16389J
John M Essigmann / Bogdan I Fedeles / Sorin Fedeles / Stefan Somlo / Robert Croy
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Single Wall Carbon Nanotubes as In Vivo Sensors

Technology / Case number: #16531
Michael S. Strano / Nigel Reuel / Thomas McNicholas / Nicole Iverson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Diminished Proteolytic Shedding of Receptor Tyrosine Kinases Mediates MEK Inhibitor Resistance in Triple-Negative Breast Cancer

Technology / Case number: #16742
Aaron Meyer / Miles Miller / Madeleine Oudin / Linda Griffith / Douglas Lauffenburger / Frank Gertler
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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Composite Layer Stamp

Technology / Case number: #16796KJ
David Hardt / Muhammad Hawwa / Hussain Al-Qahtani / Hassen Ouakad / Scott Nill / Larissa Nietner
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Connected World
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PolyMOFs: Hybrid Materials With Combined Gel and MOF Properties Via Metal-Ligand Coordination and Self-Assembly

Technology / Case number: #16872
Jeremiah A. Johnson / Aleksandr Zhukhovitskiy / Niels Holten-Andersen / Scott Grindy / Ken Kawamoto
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Climate Stabilization, Connected World
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High Throughput Isolation of Antigen-Specific Antibodies and Cells

Technology / Case number: #16927J
Han Wei Hou / Aniruddh Sarkar / Galit Alter / Jongyoon Han
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Salmochelin-Antibiotic Conjugates for Targeting Gram-Negative Pathogens

Technology / Case number: #16939
Tengfei Zheng / Phoom Chairatana / Elizabeth M. Nolan
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Fluorescent Metal-Based Nitric Oxide Sensor for Live Cells

Technology / Case number: #11806
Mi Hee Lim / Stephen J Lippard
Technology Areas: Chemicals & Materials / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Self-Assembling Peptides Incorporating Modifications and Methods of Use Thereof

Technology / Case number: #12321XE
Akihiro Horii / Fabrizio Gelain / Xiumei Wang / Shuguang Zhang
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Extended Transient Transfection by Repeated Delivery of RNA

Technology / Case number: #13415
Matthew Angel / Mehmet Yanik
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Surface Binding of Nanoparticles-Based Drug Delivery to Tissue

Technology / Case number: #15731
Rohit N Karnik / Cliff Wong / Ambika Bajpayee / Alan Grodzinsky / Moungi G Bawendi
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Nanoparticle Technology for Immune Response Against Small and Macromolecules-Method of Preparation and Uses Thereof

Technology / Case number: #13399J
Frank Alexis / Pamela Basto / Ulrich Von Andrian / Elliot Moseman / Matteo Iannacone / Jinjun Shi / Elena Tonti / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Glycan-Receptor Binding of the Novel Influenza A Virus H7N9 Hemagglutinin

Technology / Case number: #16359
Akila Jayaraman / Kannan Tharakaraman / Nathan Stebbins / Rahul Raman / Ram Sasisekharan
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Brd4 as a Prognostic Indicator and Modulator of the Cell Response to DNA Damage

Technology / Case number: #15011
Scott Floyd / Michael Yaffe
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Metamaterials Incorporating "Smart" Elements: Gyromagnetism in the Absence of a Magnetic Field

Technology / Case number: #15022
Zheng Wang / Zhiyu Wang / Lixin Ran / John D Joannopoulos / Marin Soljacic
Technology Areas: Chemicals & Materials / Communication Systems / Electronics & Photonics
Impact Areas: Connected World
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Vaccine Nanotechnology and Uses Thereof

Technology / Case number: #12788J
Frank Alexis / Liangfang Zhang / Pamela Basto / Ulrich Von Andrian / Tobias Junt / Elliot Moseman / Matteo Iannacone / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Biomarkers and Therapeutics for Autism Spectrum Disorders

Technology / Case number: #13589P
Damon Page / Mriganka Sur
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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