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Structure-Guided Chemical Modification of Guide RNA and its Applications

Technology / Case number: #19175V
Robert Langer / Hao Yin / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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User-Friendly and Easily-Accessible Synthetic Hydrogels for Biomaterials Application

Technology / Case number: #20694
Robert Langer / Marion Paolini / Jason Andresen / Owen Fenton
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Thin-film Nanocomposite Membranes for Separating Ions and Uncharged Species in Water

Technology / Case number: #24335
Zachary P Smith / Gang Han
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Magnetically Responsive Inks for 3D Printing

Technology / Case number: #21387LJ
Theodore Fedynyshyn / Brad Duncan / Jennifer Lewis
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
Labels
  • Additive Manufacturing
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Ionizable Lipids for Messenger RNA Delivery

Technology, Tangible Property / Case number: #24861
Daniel Anderson / Idris Raji / Jacob Witten
Technology Areas: Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Thermo-Responsive, Inflammation-Targeting (TRIT) Hydrogel Formulations for Local Drug Delivery in Intestinal Inflammation

Technology / Case number: #19181J
Robert Langer / Joshua Korzenik / Ashok Kakkar / Sufeng Zhang / Giovanni Traverso
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Hybrid Materials with Living Cells and Tough Hydrogels

Technology / Case number: #18548
Timothy K Lu / Tzu-Chieh Tang / Xinyue Liu / Eleonore Tham / Xuanhe Zhao
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Printing Ferromagnetic Domains in Programmable Soft Materials to Achieve Untethered Fast Transformation

Technology / Case number: #20025
Xuanhe Zhao / Yoonho Kim / Hyunwoo Yuk
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Functional Tough Bonding of Hydrogels on Various Rigid Solids

Technology / Case number: #17946
Xuanhe Zhao / German Parada Hernandez / Teng Zhang / Hyunwoo Yuk / Shaoting Lin
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Advanced Materials
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Single Administration, Multi-Dose, Multi-Therapeutic Capable Delivery Platform for Veterinary Applications

Technology / Case number: #20943J
Robert Langer / Tiffany Hua / Miguel Jimenez / Jason Li / Jacob Coffey / Michael Williams / Christoph Winfried Johannes Steiger / Ester Caffarel Salvador / Alex Abramson / Giovanni Traverso
Technology Areas: Agriculture & Food / Biotechnology
Impact Areas: Healthy Living, Advanced Materials
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Synthesis of Ester, Carbonate, and Carbamate-derived Novel Biodegradable Ionizable Lipids from Methyl Ricinoleate or Methyl 12-Hydroxystearate and its Applications

Technology / Case number: #23381Q
Daniel Anderson / Jacob Witten / rajith manan / Akiva Gordon / Bowen Li / Luke Rhym
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Design of a Soft Robot for Missions In Small Diameter Water Pipelines

Technology, Tangible Property / Case number: #19144C
Kamal Youcef-Toumi / Solene Demay / You Wu
Technology Areas: Agriculture & Food / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Synthesis and Application of Light Management with Thermochromic Hydrogel Microparticles

Technology / Case number: #20597J
Xuanlai Fang / Shien-Ping Feng / Chang Liu / Xinhao Li
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Chemiresistive CO2 Sensor

Technology / Case number: #20865J
Timothy Manning Swager / Gary Walsh / Bora Yoon
Technology Areas: Agriculture & Food / Chemicals & Materials
Impact Areas: Sustainable Future
Labels
  • CO2 Capture
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Dual Electron/Lithium Ion Conductive Polymer Composite

Technology / Case number: #19054V
Paula Hammond / Michael McDonald
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Compliant Nanostructured Surfaces with Electrically Switchable Adhesion

Technology / Case number: #19063J
Anastasios John Hart / Yijie Jiang / Kevin Turner / Sanha Kim
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Single-shot 16-fold Expansion Microscopy (16ExM)

Technology / Case number: #24859MH
Edward Stuart Boyden / Harley Yoder / Yixi Liu / Shiwei Wang / Tay Won Shin / Laura L Kiessling
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Soft Robotic, 3D-Printed Simulator of Heart Function and Disease

Technology / Case number: #25013J
Ellen Roche / Debkalpa Goswami / Christopher Nguyen / Sophie Wang / Jean Bonnemain / Luca Rosalia / Caglar Ozturk
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Ultrastructural Membrane Expansion Microscopy

Technology / Case number: #25088HM
Edward Stuart Boyden / Tay Won Shin
Technology Areas: Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Mechanophore Crosslinkers for Tough, Crosslinked Polymers

Technology / Case number: #25162J
Jeremiah A. Johnson / Zhen Sang / Grace Yao / Shu Wang / Thi Thu Suong Nguyen / Stephen Craig / Abraham Herzog-Arbeitman
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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