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Development of Multi-Specific Antibody-Serum Albumin Fusion Proteins Targeting Multiple Human and Murine CXC (ELR+) Chemokines

Technology / Case number: #19355JQ
Karl Dane Wittrup / Andrew Luster / Alessandro Angelini
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Discovery of Self-Labeling Miniproteins

Technology / Case number: #18742
Bradley L. Pentelute / Ethan Evans
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Uncharted Frontiers, Advanced Materials
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METRAN - Software for 13C-metabolic Flux Analysis

Software / Case number: #12397
Technology Areas: Biotechnology / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Connected World
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Manufacture of Thermo-Responsive Hydrogel Composing of Drug-Nanocapsule for Sustainable Release of Ibuprofen, Ofloxacin and Dexamethasone

Technology / Case number: #18561
Jeremiah A. Johnson / Farrukh Vohidov / Qixian Chen
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Structured DNA Conjugates

Technology / Case number: #18588
Mark Bathe / Hyungmin Jun / Tyson Shepherd / Remi Veneziano / Sakul Ratanalert
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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High Molecular Weight, Post-Translationally Modified Proteins Brushes Through Tyrosine Modification Chemistry

Technology / Case number: #17927
Bradley D. Olsen / Brian Seifried
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods for Conversion of Food Waste to Chemical Products

Technology / Case number: #17870
Gregory Stephanopoulos / Kristen Fortnam / Devin Currie
Technology Areas: Agriculture & Food / Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future
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Polymers for Selective Heavy Metal Removal

Technology / Case number: #19629
Timothy Manning Swager / Wen Jie Ong
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Dendrimer Drug Conjugates for Sustained Intra-Articular Delivery

Technology / Case number: #19214
Paula Hammond / Brett Geiger
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Highly Parallel Enzymatic DNA Synthesis Using Electrowetting Droplet Technology

Technology / Case number: #19620
Mark Bathe / Joseph Berleant / James Banal / Tyson Shepherd
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods for Gene Delivery with Papillomaviruses

Technology / Case number: #21704
Omar Abudayyeh / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Novel Peptidic Agents for Targeting Chemoresistant Anti-Apoptotic Mcl-1

Technology / Case number: #17695J
Amy Keating / Loren Walensky / Greg Bird / Raheleh Rezaei Araghi
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Removal of Ruthenium-Initiator from Brush-Arm Star Polymers (BASPs) via Core-to-Surface Ring-Opening Methathesis Polymerization (ROMP)

Technology / Case number: #19525
Jeremiah A. Johnson / Matthew Golder
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Sequence-Defined Chiral Poly(triazoles)

Technology / Case number: #17658
Jeremiah A. Johnson / Angela Gao / Yivan Jiang / Deborah Ehrlich (Choi) / Jonathan Barnes
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Magnetic Nanodiscs Mediate Remote Magnetomechanical Control of Neural Calcium

Technology / Case number: #20085
Polina Anikeeva / Pooja Reddy / Danijela Gregurec / Alexander Senko
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Advanced Materials
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Streptococcus Canis Cas9 for Tunable Genome Engineering and Regulation

Technology / Case number: #19757XTE
Joseph Jacobson / Pranam Chatterjee / Noah Jakimo
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers, Sustainable Future
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RNA-Based Regulatory Technologies for Improved miRNA Sensors

Technology / Case number: #19686
Ron Weiss / Jin Huh / Kevin Lebo
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Novel Peptidic Agents for Targeting Chemoresistant Anti-Apoptotic Bfl-1

Technology / Case number: #18607
Amy Keating / Justin Jenson
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Ultrasensitive and Self-Powered PDVF Nanofiber Strain Sensors

Technology / Case number: #17485JDE
Michael S. Triantafyllou / Mohsen Asodnia Fasd Johromi / Ajay Kottapalli / Jianmin Miao
Technology Areas: Biotechnology / Chemicals & Materials / Electronics & Photonics
Impact Areas: Healthy Living, Advanced Materials
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Fine-Tuning pKa's of Nucleoside Analogs to Increase Mutagenicity; a Strategy to Develop More Potent Lethal Mutagen with Anti-Viral or Anticancer Properties

Technology / Case number: #17657
John M Essigmann / Sam Peng / Vipender Singh / Bogdan I Fedeles / Andrei Tokmakoff
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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