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Computationally Engineering Integrase Variants with Improved Activity

Technology / Case number: #25676
Omar Abudayyeh / Jonathan Gootenberg / Kaiyi Jiang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods for Detecting Objects-of-Interest in Underwater Environments

Technology / Case number: #19215L
Michael Chan / Daniel Scarafoni / Alexander Bockman
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Sensing & Imaging
Impact Areas: Uncharted Frontiers, Connected World
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Loading Classical Data Into a Quantum Computer

Technology, Software / Case number: #20022L
Timothy Braje / John Cortese
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Electronics & Photonics
Impact Areas: Connected World, Advanced Materials
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Chemical Labeling and Identification via Chemical Featurization, Machine Learning, and Graph Analysis

Technology / Case number: #25563
Brett McGuire / Zachary Fried
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Connected World
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All-to-All Connected Ising Machines with Free-Space Optical Interconnects

Technology / Case number: #21178L
William Herzog / Jeffrey Chou / Suraj Bramhavar / Siddhartha Ghosh
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Industrial Engineering & Automation
Impact Areas: Connected World
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Methods And Compositions For High-Throughput Compressed Screening For Therapeutics

Technology / Case number: #21936RH
Alexander Shalek / Benjamin Mead / Conner Kummerlowe / No Inventor
Technology Areas: Computer Science / Therapeutics
Impact Areas: Healthy Living
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Improving Statistical Model-Based Speech Enhancement with Deep Neural Networks

Technology / Case number: #21028L
Bengt Borgstrom / Michael Brandstein / Robert Dunn
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Communication Systems / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living, Connected World, Advanced Materials
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A Stretchable, Wearable Ultrasound Transducer for Wide-Scale Breast Cancer Data Collection

Technology / Case number: #20934TE
Canan Dagdeviren / Lin Zhang
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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PRUNE: Prioritizing Risk for Unmitigated Network Exploitables

Technology / Case number: #20440L
Pierre Trepagnier / Dennis Ross / Allan Wollaber
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science
Impact Areas: Connected World
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CRISPR-based Diagnostics for Transplantation Medicine

Technology / Case number: #21752J
James Collins / Leonardo Riella / Michael Kaminski
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Tri-Functional Hydrophilic Self-Crosslinked Dimethylacrylamide Polymer

Technology / Case number: #18698TEM
Edward Boyden / Linyi Gao / Ruixuan Gao / Nikita Obidin
Technology Areas: Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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TOX Inhibitor and Molecular Glue

Technology / Case number: #25241
Angela Koehler / Bocheng Wu
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods and Apparatuses to Track Hand Configurations based on Ultrasound Signals

Technology / Case number: #25586
Xuanhe Zhao / Gengxi Lu
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living, Connected World
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Learning-Guided Electron Microscopy

Technology / Case number: #21380J
Yaron Meirovitch / Aravinathan Samuel / Lu Mi / Jeff Lichtman / Nir Shavit
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Healthy Living, Uncharted Frontiers
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matthew Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
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Universal GRAND Decoder

Technology / Case number: #22356J
Kenneth Duffy / Rabia Yazicigil Kirby / Amit Solomon / Vaibhav Bansal / Wei An / Muriel Medard
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Connected World, Advanced Materials
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End-to-End Research and Development Assistance through First-Principles Model-Based Reasoning and Intelligent Test & Measurement

Technology / Case number: #25660
Dirk Englund
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Industrial Engineering & Automation
Impact Areas: Connected World, Advanced Materials
License

Deep Compositional Robotic Planners that Follow Natural Language Commands

Technology / Case number: #21815
Andrei Barbu / Yen-Ling Kuo / Boris Katz
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Industrial Engineering & Automation
Impact Areas: Uncharted Frontiers, Connected World
License

Efficient Module-Level Dynamic Analysis for Dynamic Languages with Module Recontextualization

Technology / Case number: #23551
Nikolaos Vasilakis / Martin Rinard
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Connected World
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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